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A case of large intestinal malignant lymphoma
S Tsuchimoto1, T Katayama, K Itoh
1Dept. of Surgery, Hokkaido University School of Medicine.
Summary
Primary large intestinal malignant lymphoma is rare, with most cases in the stomach or small intestine. This report details a cecal follicular lymphoma case and literature review, highlighting a successful treatment outcome.
Area of Science:
- Gastroenterology
- Oncology
- Pathology
Background:
- Primary malignant lymphoma of the gastrointestinal tract is uncommon, with the stomach and small intestine being the most frequent sites.
- Primary large intestinal malignant lymphoma is particularly rare, with only 130 reported cases in Japan.
Observation:
- A 63-year-old female presented with fever and progressive right lower abdominal pain.
- Imaging revealed a cecal tumor, leading to ileocecal excision.
- Histopathology confirmed a 4 x 4.5 cm follicular lymphoma (partial type, medium-sized cell) of the cecum.
Findings:
- The resected tumor was diagnosed as follicular lymphoma, medium-sized cell type.
- Post-operative treatment with cyclophosphamide (100 mg/day for six weeks) was administered.
Implications:
- This case contributes to the limited literature on primary large intestinal lymphomas.
- The successful treatment suggests cyclophosphamide as a potential therapeutic option for cecal follicular lymphoma.
- Further research is warranted to understand the optimal management of this rare condition.