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Endoscopic optical coherence tomography angiography using a forward imaging piezo scanner probe.

Lara M Wurster1,2, Ronak N Shah3, Fabian Placzek1

  • 1Center for Medical Physics and Biomedical Engineering, Medical University of Vienna, Vienna, Austria.

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|January 18, 2019
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A novel endoscopic optical coherence tomography angiography (OCTA) system uses a piezoelectric fiber scanner for high-resolution imaging. This technology visualizes microvasculature, offering potential for early disease diagnosis in internal organs.

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Area of Science:

  • Biomedical Optics
  • Medical Imaging
  • Endoscopy

Background:

  • Development of a forward imaging endoscope for optical coherence tomography angiography (OCTA).
  • Integration of an akinetic light source (1300 nm center wavelength, 90 nm bandwidth) and a piezoelectric fiber scanner.
  • Utilizes a high A-line rate (173 kHz) for efficient imaging.

Discussion:

  • Operates in contact mode to minimize motion artifacts, crucial for OCTA.
  • Achieves 12 μm transversal resolution with a compact 4 mm diameter probe.
  • Employs a spiral scan pattern (360 Hz) for a 1.3 mm field of view.

Key Insights:

  • Demonstrates 2D and 3D OCT imaging of human finger and palm microvasculature.
  • Combines morphological tissue contrast with dynamic blood flow information.
  • Highlights the potential for improved early diagnostics of internal organ diseases.

Outlook:

  • Endoscopic OCTA offers a promising tool for non-invasive in-vivo imaging.
  • Potential applications in early detection of diseases like bladder cancer.
  • Further development could enhance diagnostic capabilities for various internal conditions.