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Updated: Aug 15, 2026

Comprehensive Protocol to Sample and Process Bone Marrow for Measuring Measurable Residual Disease and Leukemic Stem Cells in Acute Myeloid Leukemia
Published on: March 5, 2018
Bone marrow examination in the diagnosis of acute and chronic leukemias
1Department of Pathology, University of New Mexico School of Medicine, Albuquerque.
Abstract:
This article presents a brief review of the morphologic and cytochemical features of acute and chronic leukemias, followed by a discussion about new techniques that can be applied to the diagnosis of leukemias. The four techniques described include immunophenotyping, DNA content and cell cycle analysis, cytogenetics, and molecular studies. The utility of these specialized techniques in establishing a diagnosis of leukemia and in predicting prognosis is presented.
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