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Prospective, Randomized, and Controlled Study of a Human Umbilical Cord Mesenchymal Stem Cell Injection for Treating Diabetic Foot Ulcers
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Feasibility of a Low-Intensity, Technology-Based Intervention for Increasing Physical Activity in Adults at Risk for
Kristin L Schneider1, Ryan T Crews1, Vasanth Subramanian1
11 Rosalind Franklin University of Medicine and Science, North Chicago, IL, USA.
A technology-based program to increase physical activity in adults at risk for diabetic foot ulcers (DFU) was feasible and acceptable. Participants increased daily steps and improved glycemic control, suggesting potential for DFU prevention.
Area of Science:
- Podiatry and Diabetes Management
- Behavioral Science and Health Technology
- Preventive Medicine and Public Health
Background:
- Diabetic foot ulcers (DFUs) affect 19-34% of adults with diabetes, increasing amputation risk and healthcare costs.
- Gradual increases in physical activity may help prevent DFUs.
- A low-intensity, technology-based intervention was developed to promote physical activity in adults at risk for DFUs.
Purpose of the Study:
- To examine the feasibility and acceptability of a technology-based behavioral intervention designed to increase physical activity in adults at risk for diabetic foot ulcers (DFUs).
- To assess the intervention's impact on physical activity levels, daily mobility, and glycemic control (A1C).
Main Methods:
- A mixed-methods study involving 12 participants at risk for DFU (66% female, mean age 59.9 years).
- Participants received in-person counseling and used an activity monitor and text messages for 2-3 weeks, followed by 8 weeks of monitoring.
- Assessments included accelerometer-measured activity, daily mobility, A1C, and treatment acceptability via questionnaires and interviews.
Main Results:
- The intervention demonstrated feasibility, with high attendance, activity monitor usage, and text message response rates.
- Treatment acceptability was high (average rating 4.79/5).
- Participants increased daily steps by 881.89 steps/day and showed a decrease in A1C by 0.33%; daily mobility did not significantly change.
Conclusions:
- A minimally intensive, technology-based intervention may be beneficial for increasing physical activity in individuals at risk for DFUs.
- Future research should compare this intervention to usual care.
- Participant feedback suggested improvements such as providing more physical activity information and addressing pain.
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