Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Clinical Applications of Epidermal Stem Cells01:19

Clinical Applications of Epidermal Stem Cells

3.3K
Epidermal stem cells (EpiSCs) are mainly located at the basal layer of the epidermis. These cells repair minor injuries of the skin and replace dead skin cells. However, EpiSCs’ cannot heal severe wounds such as major burns or those from diabetes or hereditary disorders. In such cases, culturing the epidermal stem cells from the patient is possible and has yielded successful treatment options, such as laboratory-grown skin grafts. These grafts are synthesized using a patient’s own...
3.3K
Nursing Clinical Information System01:27

Nursing Clinical Information System

1.3K
Nursing Clinical Information System (NCIS)
A Nursing Clinical Information System (NCIS) is a specialized type of healthcare information system tailored to meet the unique needs of nursing practice. It incorporates the principles of nursing informatics to streamline information management and improve the quality of care delivery.
Critical attributes of NCIS include:
1.3K
Clinical Trials01:16

Clinical Trials

10.4K
Clinical trials are prospective experimental studies conducted on humans to determine the safety and efficacy of treatments, drugs, diet methods, and medical devices. Using statistics in clinical trials enables researchers to derive reasonable and accurate conclusions from the collected data, allowing them to make wise decisions in uncertain situations. In medical research, statistical methods are crucial for preventing errors and bias.
There are four phases in a clinical trial. A phase one...
10.4K
Clinical Trials: Overview01:11

Clinical Trials: Overview

4.9K
Clinical development focuses on how the drug will interact with the human body and encompasses four key phases of clinical trials, each serving a specific purpose in assessing the safety and effectiveness of new drugs. These phases overlap and build upon one another. Phase I involves a small group of healthy volunteers (typically 20-80 individuals) or, in cases where significant toxicity is expected, patients with the targeted disease, such as cancer or AIDS. The volunteers are tested for...
4.9K
Changes in Skin Color: Clinical Perspectives01:14

Changes in Skin Color: Clinical Perspectives

3.5K
The first thing a clinician sees is the skin, so the examination of the skin should be part of any thorough physical examination. Most skin disorders are relatively benign, but a few, including melanomas, can be fatal if untreated. A couple of the more noticeable disorders, albinism and vitiligo, affect the appearance of the skin and its accessory organs.
Albinism
Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. The defect is primarily...
3.5K
COPD: Pathogenesis and Clinical Features01:20

COPD: Pathogenesis and Clinical Features

1.8K
Chronic obstructive pulmonary disease (COPD) is a group of lung conditions that progressively worsen over time, including chronic bronchitis and emphysema. This cluster of diseases collectively leads to a gradual and irreversible decline in lung function over time.
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...
1.8K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A novel Chimeric Antigen Receptor (CAR) - strategy to target EGFR<sup>VIII</sup>-mutated glioblastoma cells via macrophages.

BMC cancer·2026
Same author

Performance evaluation of Stago sthemO 301 hemostasis analyzer for routine testing, coagulation factors, and inhibitors.

Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis·2026
Same author

Single-cell omics uncover gene dynamics shaping embryonic and extra embryonic lineages in pig blastocysts.

iScience·2026
Same author

Shiga Toxin-Producing <i>Escherichia coli-</i>Associated Hemolytic Uremic Syndrome in Adult Kidney Transplant Recipients.

Kidney international reports·2025
Same author

Meal-induced PYY and GLP1 secretions differently predict long-term weight loss after sleeve gastrectomy.

Clinical nutrition (Edinburgh, Scotland)·2025
Same author

Rare causes of pediatric primary adrenal insufficiency: Data from a large nationwide Tunisian cohort.

Annales d'endocrinologie·2025
Same journal

Rectovesical Fistula Following Esophageal Rupture and Sepsis.

Clinical case reports·2026
Same journal

Neorectal Perforation and Necrotizing Soft Tissue Infection of the Lower Limb Following Pelvic Reirradiation for Recurrent Rectal Cancer: A Case Report.

Clinical case reports·2026
Same journal

Unmasking the Hidden Culprit: Capsule Endoscopy Reveals Diffuse Hookworm Infestation as a Cause of Obscure Gastrointestinal Bleeding and Refractory Anemia-A Case Report.

Clinical case reports·2026
Same journal

Stroke-Mimic: An Intracranial Dural Arteriovenous Fistula Revealed by New-Onset Seizures and Post-Ictal Deficit.

Clinical case reports·2026
Same journal

Fournier's Gangrene and Purulent Peritonitis as a Result of Progressing Ischiorectal Abscess: A Case Report From Muhimbili National Hospital, Tanzania.

Clinical case reports·2026
Same journal

Brexpiprazole and Quetiapine Use During Pregnancy and Lactation: A Case Report.

Clinical case reports·2026
See all related articles

Related Experiment Video

Updated: Jan 30, 2026

Assessment of the Metabolic Profile of Primary Leukemia Cells
06:21

Assessment of the Metabolic Profile of Primary Leukemia Cells

Published on: November 21, 2018

11.0K

Clinically silent indolent T-cell leukemia.

Clément Janot1, Joffrey Feriel1,2, Claire Borie1,2

  • 1Division of Hematology Centre Hospitalier Universitaire Université Paris Sud 11 Le Kremlin Bicêtre France.

Clinical Case Reports
|January 19, 2019
PubMed
Summary
This summary is machine-generated.

A rare T-cell prolymphocytic leukemia case presented without symptoms, highlighting the importance of blood smear analysis for diagnosing lymphocytosis. This emphasizes the need for careful monitoring of such uncommon leukemia presentations.

Keywords:
Cellular hematologyT‐cell leukemiaT‐cell prolymphocytic leukemiaindolentlymphoid neoplasms

More Related Videos

Pre-clinical Evaluation of Tyrosine Kinase Inhibitors for Treatment of Acute Leukemia
10:49

Pre-clinical Evaluation of Tyrosine Kinase Inhibitors for Treatment of Acute Leukemia

Published on: September 18, 2013

18.6K
Murine Model of Leukemia Relapse to Induction Chemotherapy for Acute Lymphoblastic Leukemia
08:31

Murine Model of Leukemia Relapse to Induction Chemotherapy for Acute Lymphoblastic Leukemia

Published on: October 17, 2025

685

Related Experiment Videos

Last Updated: Jan 30, 2026

Assessment of the Metabolic Profile of Primary Leukemia Cells
06:21

Assessment of the Metabolic Profile of Primary Leukemia Cells

Published on: November 21, 2018

11.0K
Pre-clinical Evaluation of Tyrosine Kinase Inhibitors for Treatment of Acute Leukemia
10:49

Pre-clinical Evaluation of Tyrosine Kinase Inhibitors for Treatment of Acute Leukemia

Published on: September 18, 2013

18.6K
Murine Model of Leukemia Relapse to Induction Chemotherapy for Acute Lymphoblastic Leukemia
08:31

Murine Model of Leukemia Relapse to Induction Chemotherapy for Acute Lymphoblastic Leukemia

Published on: October 17, 2025

685

Area of Science:

  • Hematology
  • Oncology

Background:

  • Lymphocytosis, an elevation in lymphocytes, can present asymptomatically.
  • T-cell prolymphocytic leukemia (T-PLL) is an uncommon and aggressive lymphoid malignancy.

Observation:

  • The case involved a clinically silent, symptom-free presentation of T-cell prolymphocytic leukemia.
  • Routine blood smear analysis was crucial in identifying the emergent lymphocytosis.

Findings:

  • The analysis of the blood smear confirmed the diagnosis in this asymptomatic case.
  • This case underscores the diagnostic value of peripheral blood examination in detecting subtle hematological abnormalities.

Implications:

  • Highlights the critical role of routine blood smear analysis in the early detection of lymphocytosis, even in asymptomatic individuals.
  • Underscores the need for established protocols for monitoring and follow-up of rare T-cell prolymphocytic leukemia presentations.