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Published on: January 27, 2018
Acute Dystonia Secondary to Domperidone in a Pediatric Patient
Amir Shahbaz1, Karam Elahi2, Muhammad Affan3
1Internal Medicine, Icahn School of Medicine at Mount Sinai/Queens Hospital Center, New York, USA.
Abstract:
Domperidone is a dopamine-2 receptor (D2) antagonist. It is used as an antiemetic and has an excellent safety profile. We present a case of acute dystonia secondary to domperidone use in an 11-year-old girl. She was admitted with the diagnosis of viral gastroenteritis and received domperidone for persistent vomiting along with other supportive measures. The vomiting subsided with treatment, but she developed acute dystonia. Domperidone discontinued, and her condition improved in the next 24 hours. The patient discharged, and on a follow-up visit, she was asymptotic. A review of the literature suggests a possible association of acute dystonia with domperidone in children.
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