Cervical Cancer, Version 3.2019, NCCN Clinical Practice Guidelines in Oncology

Area of Science:

• Oncology
• Gynecology
• Public Health

Background:

• Cervical cancer is a significant global health concern, ranking as the fourth most common cancer in women worldwide.
• Despite being largely preventable through HPV vaccination and screening, inadequate protocols contribute to its prevalence.
• Early detection and treatment of precancerous lesions are crucial for reducing cervical cancer incidence.

Purpose of the Study:

• To provide evidence-based recommendations for the diagnosis, evaluation, and treatment of cervical cancer.
• To outline guiding principles for the workup and staging of early stage and locally advanced cervical cancer.
• To present the evidence supporting NCCN Guidelines for Cervical Cancer management.

Main Methods:

• Review of current evidence and clinical data related to cervical cancer management.
• Development of consensus-based recommendations for diagnosis and treatment.
• Focus on guiding principles for workup, staging, and treatment of early and locally advanced disease.

Main Results:

• Established protocols for the diagnosis and evaluation of cervical cancer.
• Recommendations for the treatment of early stage and locally advanced cervical cancer.
• Evidence supporting the outlined management strategies.

Conclusions:

• Cervical cancer management requires adherence to established screening and treatment protocols.
• Early stage and locally advanced cervical cancer have specific evidence-based treatment guidelines.
• Consistent application of guidelines can improve patient outcomes and reduce global burden.