Endocuff Vision Reduces Inspection Time Without Decreasing Lesion Detection: A Clinical Randomized Trial

Area of Science:

• Gastroenterology
• Medical Devices
• Endoscopy

Background:

• Mucosal exposure devices can enhance lesion detection during colonoscopy.
• Previous uncontrolled studies suggested reduced examination times with these devices.

Purpose of the Study:

• To compare the effectiveness of Endocuff Vision versus standard colonoscopy in reducing withdrawal time.
• To determine if Endocuff Vision allows complete mucosal inspection in a shorter time without impairing lesion detection.

Main Methods:

• A randomized trial involving adults over 40 undergoing screening or surveillance colonoscopies.
• Participants were assigned to either the Endocuff Vision group (n=101) or the standard colonoscopy group (n=99).
• Inspection time was measured by subtracting non-inspection activities from total withdrawal time.

Main Results:

• Mean inspection time was significantly shorter with Endocuff Vision (6.5 min) compared to standard colonoscopy (8.4 min; P < .0001).
• While not statistically significant, Endocuff Vision showed higher numbers and detection rates for adenomas and sessile serrated polyps.
• No significant differences in lesion detection were observed when controlling for demographic factors.

Conclusions:

• Endocuff Vision inclusion in screening or surveillance colonoscopies decreases examination time.
• The use of Endocuff Vision does not reduce, and may potentially improve, lesion detection rates.