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Updated: Jan 30, 2026

Implantation and Monitoring by PET/CT of an Orthotopic Model of Human Pleural Mesothelioma in Athymic Mice
Published on: December 21, 2019
A direct volume rendering visualization approach for serial PET-CT scans that preserves anatomical consistency
Younhyun Jung1, Jinman Kim2, Lei Bi1
1Biomedical & Multimedia Information Technology Research Group, School of Computer Science, The University of Sydney, Sydney, Australia.
Purpose:
Our aim was to develop an interactive 3D direct volume rendering (DVR) visualization solution to interpret and analyze complex, serial multi-modality imaging datasets from positron emission tomography-computed tomography (PET-CT).
Methods:
Our approach uses: (i) a serial transfer function (TF) optimization to automatically depict particular regions of interest (ROIs) over serial datasets with consistent anatomical structures; (ii) integration of a serial segmentation algorithm to interactively identify and track ROIs on PET; and (iii) parallel graphics processing unit (GPU) implementation for interactive visualization.
Results:
Our DVR visualization more easily identifies changes in ROIs in serial scans in an automated fashion and parallel GPU computation which enables interactive visualization.
Conclusions:
Our approach provides a rapid 3D visualization of relevant ROIs over multiple scans, and we suggest that it can be used as an adjunct to conventional 2D viewing software from scanner vendors.
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