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Updated: Jan 30, 2026

Modeling Spontaneous Metastatic Renal Cell Carcinoma mRCC in Mice Following Nephrectomy
Published on: April 29, 2014
RAB27A is an independent prognostic factor in clear cell renal cell carcinoma
Hyo Jung An1,2, Dae Hyun Song2,3,4, Hyun Min Koh2
1Department of Medicine, Gyeongsang National University College of Medicine, Jinju, Korea.
Aim:
To examine the expression of RAB27A and RAB27B in clear cell renal cell carcinoma (CCRCC).
Materials & Methods:
The intensity and proportion of tumor cells staining positive for RAB27A and RAB27B in a total of 304 cores were evaluated.
Results:
The T stage showed a significant correlation with RAB27A intensity (p < 0.001). In multivariate analysis, CCRCC with negative intensity of RAB27A expression demonstrated poor disease-specific survival (hazard ratio: 6.821, 95% CI: 1.128-41.241; p-value = 0.036).
Conclusion:
RAB27A is an independent prognostic factor in CCRCC.
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