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Updated: Jan 30, 2026

Generation of Alginate Microspheres for Biomedical Applications
Published on: August 12, 2012
Electrospraying an enabling technology for pharmaceutical and biomedical applications: A review
Sunil Kumar Boda1, Xiaoran Li2, Jingwei Xie1
1Department of Surgery-Transplant and Mary & Dick Holland Regenerative Medicine Program, College of Medicine, University of Nebraska Medical Center, Omaha, Nebraska 68198, United States.
Electrospraying (ES) fabricates micro- and nanoparticles for diverse applications. This review highlights ES fundamentals, parameters, and its use in drug delivery, biomedical imaging, and tissue engineering.
Area of Science:
- Materials Science
- Chemical Engineering
- Biotechnology
Background:
- Electrospraying (ES) is a versatile technique for creating micro- and nanoparticles.
- ES offers control over material properties like size, morphology, and composition.
- It is widely used in pharmaceutical and biomedical fields.
Purpose of the Study:
- To provide an introduction to the fundamentals of electrospraying.
- To outline experimental parameters for controlling micro- and nanoparticle fabrication.
- To review the applications of electrosprayed materials in various biomedical fields.
Main Methods:
- Review of electrospraying principles and physics.
- Discussion of key experimental parameters influencing material properties.
- Compilation of applications in drug delivery, biomedical imaging, tissue engineering, and sensing.
Main Results:
- Electrospraying enables precise control over micro- and nanoparticle characteristics.
- A wide array of materials can be fabricated using ES.
- Electrosprayed materials show significant potential in advanced biomedical applications.
Conclusions:
- Electrospraying is a powerful technology for fabricating tailored micro- and nanostructured materials.
- Its flexibility makes it ideal for developing advanced materials for the pharmaceutical and biomedical sectors.
- Further exploration of ES is encouraged for novel applications in healthcare and beyond.
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