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[Urachal transitional cell carcinoma invading the sigmoid colon]
1Department of Urology, Yokosuka National Hospital.
Hinyokika Kiyo. Acta Urologica Japonica
|June 1, 1988
Summary
This case report details a rare urachal transitional cell carcinoma invading the sigmoid colon in a 42-year-old male. Surgical intervention and combination chemotherapy led to a positive outcome with no recurrence at one year.
Area of Science:
- Urology
- Oncology
- Surgical Pathology
Background:
- Urachal carcinoma is a rare malignancy arising from remnants of the urachus.
- Transitional cell carcinoma is the most common histological type of urachal cancer.
Observation:
- A 42-year-old male presented with micturition pain.
- A large urachal transitional cell carcinoma (Grade III) invading the sigmoid colon was diagnosed.
- Surgical resection included cystourethrectomy, urachal excision, lymphadenectomy, and sigmoid colon resection with colorectostomy.
Findings:
- Histological examination confirmed transitional cell carcinoma invading the urachus and sigmoid colon.
- No lymph node metastasis was detected.
- Postoperative combination chemotherapy with 5-fluorouracil, adriamycin, and cis-platinum was administered.
Implications:
- This case highlights the importance of considering urachal carcinoma in patients with lower urinary tract symptoms and abdominal pain.
- Aggressive surgical management combined with adjuvant chemotherapy can achieve favorable outcomes in locally advanced urachal cancer.
- Further research into optimal treatment strategies for urachal transitional cell carcinoma is warranted.