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Medication-related osteonecrosis of the jaw after long-term bisphosphonate treatment in a cat
Melinda J Larson1, Ashley B Oakes2, Ember Epperson3
1BluePearl Veterinary Partners, Clearwater, Florida.
Abstract:
A 12-year-old, neutered female, domestic medium hair cat was evaluated for a nonhealing, oral mucosal ulceration. The cat had a history of idiopathic hypercalcemia that had been treated with a bisphosphonate for 41 months. Oral examination identified exposed maxillary bone adjacent to a previous extraction site. Histopathology of the exposed bone and associated mucosa was most consistent with medication-related osteonecrosis of the jaw. Treatment involved both medical and surgical interventions. Oral mucosal healing occurred after 6 months of treatment.
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