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Updated: Jan 30, 2026

Near Infrared Photoimmunotherapy for Mouse Models of Pleural Dissemination
Published on: February 9, 2021
Disseminated Strongyloidiasis
Flávio Mileo Bacelar Guerreiro, Celso Tavares Sodré, Lorena Brandão Pavan
1Professor Marcia Ramos-e-Silva, MD, PhD, Rua Dona Mariana 143 / C-32, Rio de Janeiro 22280-020, Brazil; ramos.e.silva@dermato.med.br.
Abstract:
Strongyloidiasis is a parasitic infestation caused by the helminth Strongyloides stercoralis. It is essentially gastrointestinal and in general asymptomatic but can sometimes present with skin signs. Immunocompromised patients can develop the disseminated form of the disease due to the parasite's opportunistic behavior, as in cases of coinfection by the human T-lymphotropic type 1 virus (HTLV-1). This article presents a case of a patient infected with HTLV-I and Strongyloides stercoralis who developed the disseminated form. There were purpuric reticulated periumbilical lesions as well as vibices on the patient's flanks. Histopathologic exam of a skin lesion revealed the presence of larvae in the deep reticular dermis. We emphasize the relevance of awareness regarding interaction between HTLV-1 and strongyloidiasis, besides identification of the cutaneous manifestations of the disease to reach an appropriate therapeutic diagnosis.

