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Updated: Jan 30, 2026

Three-Dimensional Collagen Matrix Scaffold Implantation as a Liver Regeneration Strategy
Published on: June 29, 2021
Multiple factors affect the regeneration of liver
Gaoxiong Ouyang1, Jianyong Liu1, Peng Wang2
1. Department of Hepatobiliary Surgery, Affiliated Cancer Hospital of Guangxi Medical University, Nanning, Guangxi, China.
Objective:
To study factors affecting the liver regeneration after hepatectomy.
Methods:
With 3D reconstitution technology, liver regeneration ability of 117 patients was analysed, and relative factors were studied.
Results:
There was no statistically difference between the volume of simulated liver resection and the actual liver resection. All livers had different degrees of regeneration after surgery. Age, gender and blood indicators had no impact on liver regeneration, while surgery time, intraoperative blood loss, blood flow blocking time and different ways of liver resection had a significant impact on liver regeneration; In addition, the patients' own pathological status, including, hepatitis and liver fibrosis all had a significant impact on liver regeneration.
Conclusion:
3D reconstitution model is a good model to calculate liver volume. Age, gender, blood indicators and biochemistry indicators have no impact on liver regeneration, but surgery indicators and patients' own pathological status have influence on liver regeneration.
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