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Updated: Jan 30, 2026

Controlled Synthesis and Fluorescence Tracking of Highly Uniform PolyN-isopropylacrylamide Microgels
Published on: September 8, 2016
Temperature Dependence of Electrophoretic Mobility and Hydrodynamic Radius of Microgels of
Yasuyuki Maki1, Kentaro Sugawara2, Daisuke Nagai3
1Department of Chemistry, Graduate School of Science, Kyushu University, Fukuoka 819-0395, Japan. maki@chem.kyushu-univ.jp.
Abstract:
Electrostatic interactions in charged microgels, which are dominated by the microgel net charge, play a crucial role in colloidal stabilization and loading of small, charged molecules. In this study, the temperature dependences of electrophoretic mobility μ and hydrodynamic radius Rh were measured for a slightly ionized poly(N-isopropylacrylamide) (PNIPA) microgel in a dilute suspension. A decrease in Rh was observed in the temperature range between 30 °C and 35 °C, corresponding to the lower critical solution temperature of PNIPA, and an increase in |μ| was observed in a higher temperature range between 34 °C and 37 °C. The analysis based on electrophoresis theory for spherical polyelectrolytes indicated that the net charge of the microgel decreased as the microgel was deswollen.
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