[The diagnostic and prognostication of glaucoma.]

The glaucoma is a leading cause of irreversible blindness in all countries. In the nearest years an increasing of patients with the given pathology is prognosticated. Nowadays, development of disease is related to alteration of interleukin profile in lacrimal fluid. however, diagnostic significance of interleukins is studied insufficiently. The purpose of study. To determine diagnostic significance of interleukins on a local level for amelioration of diagnostic and prognostication of development of glaucoma. The content of interleukins in lacrimal fluid was analyzed in 80 patients with glaucoma stage II and 45 healthy individuals using technique of sandwich-linked enzyme-linked immunosorbent assay with calculation of informativeness of indices of immunity. The results. The analysis established high diagnostic significance of IL-2, IL-17, IL-8 for verification of glaucoma. They are proposed to be applied in laboratory diagnostic and prognostication of disease. The developed regression model ensures with high accuracy prognostication of development of glaucoma in case of increased level of IL-2, IL-17, IL-8.