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Updated: Jan 30, 2026

Quantification of Atherosclerosis in Mice
Published on: June 12, 2019
[Association between osteoporosis and atherosclerosis in dyslipidemia.]
1Third Department of Medicine, Teikyo University Chiba Medical Center, Ichihara, Japan.
Abstract:
Age-related osteoporosis and atherosclerosis is promoted by life style-related diseases such as dyslipidemia and diabetes mellitus. Common factors pathophysiologically involved in both osteoporosis and vascular calcification include senescent cells and osteoprotegerin(OPG). Dyslipidemia may impair both osteoclast and osteoblast function,thereby causing osteoporosis. Statins may have favorable effect on bone. Some anti-osteoporotic medications have also been suggested to show protective effect from atherosclerosis.
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