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Updated: Jan 30, 2026

Generation of Comprehensive Thoracic Oncology Database - Tool for Translational Research
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Precision oncology: as much expectations as limitations

Vitor Fiorin Vasconcellos1, Leandro Machado Colli2, Ahmad Awada3

  • 1Clinical Oncology, Instituto do Câncer do Estado de São Paulo, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, SP, Brazil.

Ecancermedicalscience
|January 26, 2019
PubMed

Insights

Next-generation sequencing (NGS) advances personalized cancer therapy. However, only a small fraction of solid tumors are currently eligible for targeted drugs, despite clinical benefits and cost-effectiveness analyses.

Area of Science:

  • Oncology
  • Genomics
  • Pharmacology

Background:

  • Recent advancements in next-generation sequencing (NGS) platforms have led to reduced costs and increased accessibility.
  • There is growing investment and research into novel cancer targets and corresponding targeted therapies.
  • Personalized anti-cancer therapies are generating significant global interest.
Keywords:
DNAmolecular diagnostic techniquesmolecular targeted therapyprecision medicinesequence analysis

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