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Basophil Activation Test for Allergy Diagnosis
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Allergy screening in a schoolchildren-based population.

Marta Sacchetti1,2, Vincenza Regine3, Flavio Mantelli4

  • 1Department of Sense Organs, University Sapienza of Rome, Rome, Italy.

Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology
|January 26, 2019
PubMed
Summary
This summary is machine-generated.

Schoolchildren screening effectively identifies children with allergic diseases. This program helps in the early detection and management of atopic conditions in young students.

Keywords:
allergic diseasesatopychildrenschool screeningscreening questionnaire

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Area of Science:

  • Pediatric Allergy and Immunology
  • Public Health Screening Programs
  • Epidemiology of Allergic Diseases

Background:

  • Early identification of allergic diseases in schoolchildren is crucial for timely intervention.
  • Screening programs can improve the management of atopic conditions in pediatric populations.
  • Understanding the prevalence and risk factors for allergies in school-aged children is essential.

Purpose of the Study:

  • To implement and evaluate a schoolchildren screening program for the early identification of allergic diseases.
  • To assess the utility of the Childhood Health Assessment (ChAt) questionnaire in identifying atopic children.
  • To investigate the association between demographic/environmental factors and allergic disease risk in children.

Main Methods:

  • A screening program was conducted in 13 primary schools in Rome, involving demographic data collection and the ChAt questionnaire.
  • Children with a suspect of allergy (ChAt score > 2) and ocular examination for allergic conjunctivitis were evaluated.
  • Allergological evaluations were performed on suspect cases, and results were correlated with demographic and environmental variables.

Main Results:

  • Out of 2667 children, 35.1% showed potential allergic disease based on ChAt scores.
  • Older age, male gender, and fewer siblings were associated with a higher risk of allergic disease.
  • Allergological evaluation confirmed allergic disease in 97% of suspect children, with 29.9% undiagnosed previously.

Conclusions:

  • Schoolchildren screening using the ChAt questionnaire is an effective tool for early identification of undiagnosed atopic children.
  • The study highlights the potential for public health initiatives to improve allergy detection in schools.
  • Early diagnosis through screening facilitates timely management and potentially better outcomes for allergic diseases in children.