Predictors of Recurrence and Complications in Pediatric Pyeloplasty

Erman Ceyhan1, Fatih Ileri1, Taner Ceylan2

  • 1Hacettepe University Faculty of Medicine, Department of Urology, Ankara, Turkey.

Urology
|January 26, 2019
PubMed

Insights

Early complications after pediatric pyeloplasty predict recurrence. Transanastomotic diversion lowers complication rates, while preoperative diversion increases both complications and recurrence risk in children.

Area of Science:

  • Pediatric Urology
  • Surgical Outcomes
  • Renal Function Preservation

Background:

  • Pyeloplasty failure in children presents significant management challenges.
  • Early detection and intervention are crucial for preserving renal function.

Purpose of the Study:

  • To identify predictors of recurrence and complications following primary pediatric pyeloplasty.
  • To evaluate the impact of different diversion techniques on outcomes.

Main Methods:

  • Retrospective analysis of 490 renal units undergoing primary dismembered pyeloplasty (June 2001-October 2016).
  • Evaluation of demographic features, operative data, clinical findings, complications, and recurrence rates.
  • Statistical analysis to determine significant predictors of recurrence and complications.

Main Results:

  • Recurrence and complication rates were 6.7% and 11.4%, respectively.
  • Early postoperative complications (7.8% UTI, 1.8% diversion-related, 1.4% urinoma) and preoperative diversion were significant predictors of recurrence.
  • Transanastomotic diversion and absence of preoperative diversion were associated with lower complication rates.

Conclusions:

  • Early postoperative complications are a key predictor of recurrence after pediatric pyeloplasty.
  • Transanastomotic diversion is associated with reduced complication rates.
  • Preoperative diversion increases both complication and recurrence rates.
Abstract

Related Concept Videos

Hemodialysis II: Procedure and Complications01:24

Hemodialysis II: Procedure and Complications

DialyzersA hemodialysis (HD) dialyzer is a plastic cartridge containing thousands of parallel hollow fibers, which serve as semipermeable membranes. These fibers are typically made from cellulose-based or other synthetic materials. During HD, blood is pumped into the top of the cartridge and distributed among these fibers. Simultaneously, dialysis fluid, known as dialysate, is introduced into the bottom of the cartridge, bathing the outside of the fibers. Across the semipermeable membrane,...
790
Pneumonia III: Complications and Assessment01:30

Pneumonia III: Complications and Assessment

Pneumonia poses the potential for numerous complications that warrant consideration. These complications include the following:
851
Diabetes: Symptoms, Diagnosis, and Complications01:15

Diabetes: Symptoms, Diagnosis, and Complications

For most patients, experiencing several weeks of polyuria, polydipsia, fatigue, and significant weight loss may indicate the presence of diabetes. Furthermore, adults displaying the phenotypic appearance of type 2 diabetes (particularly those who are obese and not initially insulin-requiring), may have islet cell autoantibodies, suggesting autoimmune-mediated β cell destruction and a diagnosis of latent autoimmune diabetes of adults (LADA). The categorization of glucose homeostasis is...
2.3K
Asthma-III: Symptoms and Complications01:24

Asthma-III: Symptoms and Complications

Asthma, a common chronic respiratory condition, is classified considering the frequency and severity of symptoms alongside lung function impairment. Understanding this classification is essential for appropriate treatment and management. Here's a detailed look at the classification of asthma and its clinical features and complications:
Classification of Asthma
3.3K
Pharmacokinetics in Pediatric Patients: Drug Excretion01:26

Pharmacokinetics in Pediatric Patients: Drug Excretion

In pediatric medicine, understanding the renal function and drug elimination nuances is crucial for administering safe and effective treatments. Newborns, in particular, display markedly slower renal functions than adults, profoundly affecting how drugs are cleared from their bodies. This slower drug clearance requires clinicians to extend the dosing intervals for many medications to prevent drug accumulation and toxicity while ensuring therapeutic efficacy.One key area where these adjustments...
259
Pharmacokinetics in Pediatric Patients: Drug Distribution01:17

Pharmacokinetics in Pediatric Patients: Drug Distribution

Drug distribution in the pediatric population exhibits unique challenges and considerations due to the physiological differences between children, particularly neonates and infants, and adults. A crucial aspect of pediatric pharmacology is understanding how these differences impact the pharmacokinetics of various drugs, necessitating age-specific dosing strategies to ensure efficacy and safety.Neonates and infants have a higher total body water content, ~75%–90% of their body weight,...
301