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Related Concept Videos

Inflammatory Bowel Disease II: Crohn's Disease01:30

Inflammatory Bowel Disease II: Crohn's Disease

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Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
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Inflammatory Bowel Disease I: Ulcerative Colitis01:27

Inflammatory Bowel Disease I: Ulcerative Colitis

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Introduction
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
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The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
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Inflammatory Bowel Disease V: Surgical Management01:21

Inflammatory Bowel Disease V: Surgical Management

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Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:
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Inflammatory Bowel Disease IV: Pharmacological Management01:29

Inflammatory Bowel Disease IV: Pharmacological Management

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Upon diagnosis, managing Inflammatory Bowel Disease (IBD) involves addressing several crucial aspects. The primary goals include resting the bowel, correcting malnutrition, and providing symptomatic relief. Resting the bowel may consist of medications to reduce inflammation and promote healing. Correcting malnutrition is essential, often requiring dietary adjustments and nutritional supplements. Symptomatic relief aims to ease pain, diarrhea, and other discomforts in IBD.
Pharmacologic...
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Bacterial Phylum Chlamydiae01:29

Bacterial Phylum Chlamydiae

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The phylum Chlamydiae or Chlamydiota is composed of a single order, Chlamydiales. This phylum consists entirely of obligate intracellular parasites that infect eukaryotic hosts. While human pathogens within this group have been studied extensively, the phylum encompasses many species capable of interacting with various eukaryotic organisms. Members of Chlamydiae are typically small cocci, approximately 0.5 μm in diameter, and exhibit a distinctive developmental cycle. As is characteristic...
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Pneumonia I: Introduction01:30

Pneumonia I: Introduction

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Pneumonia is an acute respiratory infection that targets the lungs, specifically the alveoli. These tiny air sacs, essential for oxygen exchange, become engorged with pus and fluid, severely hindering breathing, decreasing oxygen absorption, and causing significant pain and discomfort during respiration.
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Forward Genetic Approaches in Chlamydia trachomatis
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Chlamydia pneumoniae Infection and Inflammatory Diseases.

Rebecca A Porritt1, Timothy R Crother1

  • 1Division of Pediatric Infectious Diseases and Immunology, Burns and Allen Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048.

Forum on Immunopathological Diseases and Therapeutics
|January 29, 2019
PubMed
Summary
This summary is machine-generated.

Chlamydia pneumoniae, a bacterial pathogen, is studied for its role in chronic inflammatory diseases. Research explores its potential impact on conditions like atherosclerosis, with ongoing investigations into treatment strategies.

Keywords:
Alzheimer’sChlamydia pneumoniaearthritisasthmaatherosclerosiscancer

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Area of Science:

  • Infectious Diseases
  • Bacteriology
  • Immunology

Background:

  • Chlamydia pneumoniae is an obligate intracellular bacterium.
  • It disseminates throughout the host, evading immune responses.
  • Its role in chronic inflammatory diseases is under investigation.

Purpose of the Study:

  • To review the latest information on the potential role of C. pneumoniae infection in chronic inflammatory diseases.
  • To examine evidence linking C. pneumoniae to various pathologies.
  • To assess its potential as a mitigating factor in chronic inflammation.

Main Methods:

  • Review of animal model studies.
  • Analysis of human correlative studies.
  • Evaluation of antibiotic clinical trials for atherosclerosis.

Main Results:

  • Studies have investigated the link between C. pneumoniae and chronic inflammatory conditions.
  • Evidence from animal and human studies is being compiled.
  • Antibiotic trials have been conducted to explore causal relationships.

Conclusions:

  • Chlamydia pneumoniae is a significant focus in understanding chronic inflammatory diseases.
  • Further research is needed to confirm its role and potential as a therapeutic target.
  • The review synthesizes current knowledge on C. pneumoniae's involvement in pathologies.