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Diet and Metabolism in the Evolution of Asthma and Obesity
Anne E Dixon1, Fernando Holguin2
1Division of Pulmonary and Critical Care, University of Vermont, Given D209, 89 Beaumont Avenue, Burlington, VT 05482, USA.
Abstract:
Obesity is a major risk factor for asthma. This association appears related to altered dietary composition and metabolic factors that can directly affect airway reactivity and airway inflammation. This article discusses how specific changes in the western diet and metabolic changes associated with the obese state affect inflammation and airway reactivity and reviews evidence that interventions targeting weight, dietary components, lifestyle, and metabolism might improve outcomes in asthma.
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