Cherubism in 12 Year Young Female

Area of Science:

• Oral and Maxillofacial Surgery
• Genetics
• Pediatric Dentistry

Background:

• Cherubism is a rare, benign, autosomal-dominant inherited fibro-osseous jaw lesion.
• Characterized by jaw bone degradation and fibrous tissue masses, it typically self-limits and involutes by puberty.
• This condition usually presents in early childhood.

Observation:

• A nonfamilial case of cherubism in a teenage female patient is presented.
• The patient initially received calcitonin nasal spray treatment.
• Surgical resection and recontouring were performed after puberty.

Findings:

• Cherubism management may require intervention beyond the typical pubertal involution period.
• Nonfamilial cases, though rare, necessitate tailored treatment approaches.
• Combined medical and surgical interventions can be effective for cherubism post-puberty.

Implications:

• This case highlights the potential need for extended management strategies for cherubism.
• It expands understanding of cherubism's clinical course and treatment in nonfamilial teenage cases.
• Further research into long-term outcomes of surgical and medical cherubism treatments is warranted.