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MRI and Blood Flow in Human Arteries: Are There Any Adverse Effects?

K Gayathri1, K Shailendhra2

  • 1Department of Mathematics, Amrita School of Engineering, Coimbatore, Amrita Vishwa Vidyapeetham, Coimbatore, 641 112, India.

Cardiovascular Engineering and Technology
|January 30, 2019
PubMed
Abstract

Insights

High magnetic fields in MRI may affect blood flow, particularly in the pulmonary artery, necessitating careful consideration of clinical consequences. Animal studies may not accurately predict human responses to ultra-high field MRI.

Area of Science:

  • Biomedical Engineering
  • Medical Imaging Physics
  • Cardiovascular Physiology

Background:

  • Magnetic Resonance Imaging (MRI) utilizes strong magnetic fields.
  • Understanding potential adverse effects on human physiology is crucial for safety.
  • Previous studies on magnetic field effects on blood flow have yielded conflicting results.

Purpose of the Study:

  • To investigate adverse effects of high and ultra-high magnetic fields on human blood flow.
  • To quantitatively assess impacts on blood velocity and hemodynamic wall parameters.
  • To analyze effects in four major human arteries under varying magnetic field strengths.

Main Methods:

  • Approximation of arterial blood flow as flow through a rigid porous tube.
  • Utilized the McDonalds model with medical literature pressure gradient waveforms.
  • Qualitative and quantitative analysis of blood velocity, wall shear stress (WSS), oscillatory shear index (OSI), and relative residence time (RRT).

Main Results:

  • No significant changes observed up to 3 Tesla (T) in most arteries.
  • Discernible changes in velocity and RRT noted in the pulmonary artery even at lower fields.
  • Very significant changes in hemodynamic parameters observed in the pulmonary artery beyond 8T.
  • The hypothesis of co-locating low WSS and high OSI was not supported.

Conclusions:

  • Clinical consequences of ultra-high field MRI exposure require careful consideration.
  • Animal study results may not be directly applicable to human responses.
  • Further development of wall slip conditions is needed for accurate hemodynamic modeling.
Keywords:
Hemodynamic wall parametersHigh intensity static magnetic fieldInterface conditionOscillatory shear indexRelative residence timeWall shear stress

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