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Treatment resistant impetigo herpetiformis treated with infliximab
Atiye Ogrum1, Zennure Takci1, Havva Yildiz Seckin1
1Department of Dermatology and Venereology, School of Medicine, Gaziosmanpasa University, Tokat, Turkey.
Abstract:
Impetigo herpetiformis is a rare disease of pregnancy with the onset being in the second half of pregnancy and resolution after delivery. It is associated with a high rate of perinatal mortality and fetal abnormalities. Clinical and histological features of the disease are consistent with pustuler psoriasis. We reported a case of 25-year-old female gravida 1 para 0, who responded poorly to consecutive treatments with systemic steroids, cyclosporine, intravenous immunoglobulin, and acitretin. Good response was obtained with adding infliximab to the treatment.
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