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Updated: Jan 30, 2026

An Economical and Versatile High-Throughput Protein Purification System Using a Multi-Column Plate Adapter
Published on: May 21, 2021
[Multi-column technologies in chromatographic analysis]
Xiaofei Wang1, Kaiyue Sun1, Bo Zhang1
1College of Chemistry & Chemical Engineering, Xiamen University, Xiamen 361005, China.
Abstract:
Multi-column chromatographic technologies provide high throughput and high resolution separations through parallel, serial or parallel-serial column combinations. In comparison with classical single-column based chromatography, multi-column chromatography well satisfied the need for separations of large batch samples and highly complex bio-samples, and therefore attracted extensive interests. In this review, we discussed the recent developments in multi-column chromatography and its applications in multidimensional separation, chip chromatography, capillary electrophoresis, stationary-phase screening, and serial column chromatography. We also discussed the limitations and future developments in multi-column chromatography.
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