Related Experiment Video

Updated: Jan 30, 2026

Measurement of Specific Mycobacterial Mistranslation Rates with Gain-of-function Reporter Systems
06:18

Measurement of Specific Mycobacterial Mistranslation Rates with Gain-of-function Reporter Systems

Published on: April 26, 2019

6.5K

Association of Total and Trimester-Specific Gestational Weight Gain Rate with Early Infancy Weight Status: A

Jiajin Hu1,2, Izzuddin M Aris3,4,5, Emily Oken6,7

  • 1Department of Social Medicine, School of Public Health, China Medical University, Shenyang 110122, Liaoning, China. jjhu@cmu.edu.cn.

Nutrients
|January 31, 2019
PubMed

Insights

Higher gestational weight gain (GWG) is linked to increased infant BMI z-scores in the first six months. This association is primarily driven by weight gained during the first two trimesters of pregnancy.

Area of Science:

  • Maternal and Child Health
  • Pediatric Nutrition
  • Epidemiology

Background:

  • Gestational weight gain (GWG) is a critical factor influencing maternal and infant health outcomes.
  • Existing research on GWG and offspring weight status needs expansion, particularly in Asian populations.
  • Understanding the specific impact of GWG timing on infant growth is crucial for public health interventions.

Purpose of the Study:

  • To investigate the association between total and trimester-specific gestational weight gain (GWG) and offspring weight status in infancy.
  • To analyze the longitudinal impact of GWG rate on infant growth trajectories from birth to six months.
  • To identify potential differences in these associations based on maternal pre-pregnancy weight and infant sex.

Main Methods:

  • Prospective cohort study involving 801 mother-infant pairs in China.
  • Linear mixed-effects models and linear regression were used to analyze GWG rate (kg/week) against infant growth measures (BMIZ, WFAZ, LFAZ) at multiple time points.
  • Statistical analyses examined associations at birth, 1, 3, and 6 months postpartum.

Main Results:

  • A greater total GWG rate was significantly associated with higher infant BMI z-scores (BMIZ) and weight-for-age z-scores (WFAZ) throughout the first six months.
  • GWG rate during the first two trimesters, but not the third, showed a positive association with infant BMIZ.
  • The positive association between GWG rate and infant BMIZ was consistent across all measured time points and more pronounced in normal-weight mothers and male infants.

Conclusions:

  • Increased gestational weight gain rate is positively associated with higher offspring BMI z-scores in early infancy.
  • The first two trimesters appear to be the critical period for GWG's influence on infant adiposity.
  • Findings highlight the importance of monitoring and managing GWG, especially in Asian populations, to promote healthy infant growth.

Keywords:
body mass indexgestation weight gaininfancytrimester-specificweight status

More Related Videos

Use of a Hanging-weight System for Liver Ischemia in Mice05:53

Use of a Hanging-weight System for Liver Ischemia in Mice

Published on: August 7, 2012

16.5K
Use of a Hanging-weight System for Isolated Renal Artery Occlusion07:54

Use of a Hanging-weight System for Isolated Renal Artery Occlusion

Published on: July 19, 2011

16.5K

Related Concept Videos

Weighted Mean00:57

Weighted Mean

While taking the arithmetic, geometric, or harmonic mean of a sample data set, equal importance is assigned to all the data points. However, all the values may not always be equally important in some data sets. An intrinsic bias might make it more important to give more weightage to specific values over others.
For example, consider the number of goals scored in the matches of a tournament. While computing the average number of goals scored in the tournament, it may be more important to...
6.3K
Density, Specific Weight, Specific Gravity and Compressibility of Fluid01:27

Density, Specific Weight, Specific Gravity and Compressibility of Fluid

Density, specific weight, specific gravity, and compressibility are fundamental properties of fluids. Density is the mass per unit volume, characterizing the mass of a fluid system. It influences buoyancy, pressure, flow dynamics, viscosity, thermal conductivity, and sound propagation. For instance, in pipeline design, accurate density measurements ensure that the pipeline can handle the fluid's mass.
Specific weight represents the weight per unit volume and is calculated by multiplying...
1.6K
Atomic Weight01:25

Atomic Weight

Protons and neutrons have approximately the same mass, about 1.67 × 10-24 grams. Scientists arbitrarily define this amount of mass as one atomic mass unit (amu) or one Dalton. Electrons are much smaller in mass than protons, weighing only 9.11 × 10-28 grams, or about 1/1800 of an atomic mass unit. As a result, they do not contribute much to an element's overall atomic mass. This means that, when considering atomic mass, it is customary to ignore the mass of any electrons and...
12.6K
Mass and Weight01:19

Mass and Weight

Mass and weight are often used interchangeably in everyday conversation. For example,  medical records often show our weight in kilograms, but never in the correct units of newtons. In physics, however, there is an important distinction. Weight is the pull of the Earth on an object. It depends on the distance from the center of the Earth. Weight dramatically varies if we leave the Earth's surface, unlike mass, which does not vary with location. On the Moon, for example, the...
15.3K
Apparent Weight01:09

Apparent Weight

True weight is the measure of the gravitational force acting on an object. However, if the object accelerates, its measured weight is different from its true weight. Similar observations can be made when the object is submerged in water. An object's weight in water is its apparent weight, which is equal to the difference between its true weight and the buoyant forces.
Consider a person standing on a bathroom scale inside an elevator. If the scale is accurate at rest, its reading equals the...
9.8K
Cable Subjected to Its Own Weight01:13

Cable Subjected to Its Own Weight

Overhead power transmission lines rely on cables to carry electricity across large distances. To ensure the stability and functionality of these lines, it is crucial to understand the shape and tension experienced by the cables under the influence of their weight.
A generalized loading function is employed to analyze a cable subjected to its own weight. This function considers the force acting along the cable's arc length rather than its projected length, providing a more accurate...
795