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Updated: Jan 30, 2026
09:21
Optimized Management of Endovascular Treatment for Acute Ischemic Stroke
Published on: January 18, 2018
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Regional differences in ischemic stroke in India (north vs. south)
Vishnu Y Venugopalan1, Rohit Bhatia1, Jeyaraj Pandian2
1Department of Neurology, All-India Institutes of Medical Sciences, New Delhi, India.
Summary
Regional differences in stroke exist between North and South India, with distinct risk factors and outcomes. North India experienced higher mortality despite similar recovery rates, highlighting the need for tailored healthcare strategies.
Area of Science:
- Neurology
- Public Health
- Epidemiology
Background:
- India's diverse geography and populations lead to varying health risks.
- Understanding regional disparities in stroke is crucial for effective healthcare policy.
Purpose of the Study:
- To investigate and compare regional differences in stroke between North and South India.
- Analyze variations in risk factors, severity, mechanisms, management, and outcomes of ischemic stroke.
Main Methods:
- Analysis of data from the Indo-US Collaborative Stroke Project, a multicentre prospective study.
- Comparison of ischemic stroke patients from five academic centers in North and South India.
Main Results:
- North Indian patients were older, with lower rates of diabetes, dyslipidemia, tobacco, and alcohol use.
- North Indian patients had higher stroke severity scores and received more intravenous thrombolysis.
- Despite similar three-month functional outcomes, North Indian patients had significantly higher 90-day mortality.
Conclusions:
- Significant regional variations in stroke risk factors and mechanisms observed in India.
- Differences in lifestyle and acute stroke care necessitate better adherence to national guidelines.
- Addressing regional disparities can improve stroke management and reduce mortality across India.
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