Role of Non-coding RNAs in Interactions between Host and Influenza Virus

Non-coding RNAs (ncRNAs) are a class of RNAs that have no potential for protein coding. Increasing numbers of studies have provided strong evidence that ncRNAs play important roles in regulation of various biologic processes, including interactions between viruses and the host. Influenza viruses remain a major, threat to human health and animal livestock. Interactions between the host and mutations of influenza viruses are very complicated. Recent data have shown that many ncRNAs play important roles in the interactions between influenza viruses and the host. Understanding the fuiction of these ncRNAs in the infection and replication of influenza viruses is very important to elucidate the pathogenesis of these viruses, and to provide strategies for the prevention and control of influenza. This review summarizes the ncRNAs that act as key regulators of interactions between the host and influenza viruses.