Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Acute stress alters the 'default' brain processing.

Wei Zhang1, Mahur M Hashemi1, Reinoud Kaldewaij1

  • 1Donders Institute, Centre for Cognitive Neuroimaging, Radboud University, Nijmegen, the Netherlands; Behavioural Science Institute, Radboud University, Nijmegen, the Netherlands.

Neuroimage
|February 1, 2019
PubMed
Summary

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Theta burst stimulation of extrastriate body area for body perception in anorexia nervosa: a randomized controlled trial.

Translational psychiatry·2026
Same author

Altered Theory of Mind Engagement and Neural Alignment in Social Anxiety During Movie Viewing.

Biological psychiatry global open science·2026
Same author

Stimulation of the human periaqueductal gray induces threat bradycardia: a case report.

Neurocase·2026
Same author

Resting-State Functional Connectivity of the Amygdala and Hippocampus in PTSD: Results From the PGC-ENIGMA PTSD Working Group.

The American journal of psychiatry·2026
Same author

Improving Emotion Control in Social Anxiety by Targeting Rhythmic Brain Circuits.

The Journal of neuroscience : the official journal of the Society for Neuroscience·2026
Same author

Disrupted intrathalamic and thalamocortical structural covariance networks in posttraumatic stress disorder.

Network neuroscience (Cambridge, Mass.)·2026
Same journal

Lifespan Trajectories of the Brain's Functional Complexity Characterized by Multiscale Sample Entropy.

NeuroImage·2026
Same journal

Pleasant fragrance modulates dyadic social sharing of positive emotion: Sharer-centered socioemotional enhancement effect and its neural couplings.

NeuroImage·2026
Same journal

Altered Functional Hierarchical and Sequential Organization in Individuals with Schizophrenia during Auditory Processing.

NeuroImage·2026
Same journal

Mechanical Deformation Explains Distinct Neuroimaging Patterns and Etiologies in Brain Trauma.

NeuroImage·2026
Same journal

Ventral striatum temporal interference brain stimulation enhances the reward-positivity event-related potential and reduces anxiety.

NeuroImage·2026
Same journal

NeuroHarm‑Kit: An Open‑Source Toolbox for Benchmarking Deep‑Learning Harmonization of Multi‑Site T1‑Weighted MRI.

NeuroImage·2026
See all related articles
This summary is machine-generated.

Acute stress rapidly alters brain network connectivity, specifically within the salience network (SN) and default mode network (DMN), even without tasks. These brain changes correlate with individual cortisol stress responses.

Area of Science:

  • Neuroscience
  • Psychology
  • Stress Research

Background:

  • Active adaptation to acute stress is crucial for daily functioning.
  • Cortisol and large-scale brain network reallocations are implicated in stress adaptation.
  • Previous studies focused on task-related network shifts, leaving resting-state changes unclear.

Purpose of the Study:

  • To investigate stress-induced functional connectivity changes in resting-state networks (SN, CEN, DMN) without explicit task demands.
  • To determine if these network shifts predict individual variations in cortisol stress responses.

Main Methods:

  • Resting-state fMRI data from 335 healthy participants before and after a stressor (cold-pressor test and mental arithmetic task).
  • Analysis of functional connectivity changes (delta-FC) within and between SN, CEN, and DMN.
Keywords:
Functional connectivityRSNsResting-state fMRIResting-state networksStressStress reactivityStress vulnerability

Related Experiment Videos

  • Correlation analysis between cortisol increase and delta-FC.

    • Main Results:

    • Acute stress induced increased within-network connectivity in the SN.
    • Stress led to decreased local and global coupling of the DMN.
    • These connectivity changes were associated with individual cortisol stress responses.

    Conclusions:

    • Acute stress causes immediate resting-state network connectivity changes in SN and DMN, independent of ongoing tasks.
    • Brain reorganization during stress is linked to individual stress reactivity.
    • Observed network changes may serve as a neural marker for stress resilience and vulnerability.