Related Experiment Video
Updated: Jan 30, 2026
06:36
Elastic Staining on Paraffin-embedded Slides of pT3N0M0 Gastric Cancer Tissue
Published on: May 1, 2019
7.4K
[Looking back 2018--focused on gastric cancer]
1Department of Gastrointestinal Surgery,Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Peking University Cancer Hospital and Institute, Beijing 100142, China.Email:ziyu_li@hsc.pku.edu.cn.
Summary
Gastric cancer is common in China, with environmental factors and infections like H. pylori playing key roles. Recent advancements focus on molecular typing, minimally invasive surgery, and novel therapies like immunotherapy for better patient outcomes.
Area of Science:
- Oncology
- Gastroenterology
- Surgical Innovation
Background:
- Gastric cancer presents a high incidence in China, with a significant proportion of advanced cases globally.
- Environmental factors, Helicobacter pylori, and Epstein Barr virus (EBV) are established contributors to gastric cancer development.
- Molecular typing based on genetic characteristics is emerging to guide personalized treatment and prognosis.
Purpose of the Study:
- To review significant developments in gastric cancer research and treatment modalities from 2018.
- To highlight advancements in surgical techniques, molecular diagnostics, and systemic therapies.
- To provide an overview of current research hotspots and future directions in gastric cancer management.
Main Methods:
- Literature review of 2018 research on gastric cancer.
- Analysis of advancements in surgical approaches, including laparoscopy and endoscopic treatments.
- Examination of progress in chemotherapy, targeted therapy, immunotherapy, and molecular typing.
Main Results:
- Minimally invasive surgical techniques like laparoscopy are increasingly standard for early gastric cancer, improving patient quality of life.
- Comprehensive treatment combining surgery, radiotherapy, and chemotherapy is standard for locally advanced disease.
- Targeted therapy and immunotherapy offer new avenues for advanced gastric cancer treatment, including potential for conversion therapy.
Conclusions:
- Gastric cancer treatment is trending towards precision and minimally invasive approaches.
- The integration of molecular diagnostics and novel systemic therapies is expanding treatment options.
- Continued research into new drugs and treatment models is crucial for improving outcomes in advanced gastric cancer.
More Related Videos
Related Concept Videos
01:16Gastric Motility
3.1K
Gastric motility is the coordinated contraction and relaxation of stomach muscles that convert ingested food into chyme, a semi-liquid substance ready for further digestion in the intestines. The process begins with the vagus nerve inducing the relaxation of the smooth muscles in the fundus and body of the stomach, allowing these regions to expand and accommodate up to approximately 1.5 liters of food and liquid.
Peristaltic Waves and Chyme Formation
Upon food entry, the stomach initiates...
Peristaltic Waves and Chyme Formation
Upon food entry, the stomach initiates...
3.1K
01:16Gastric Emptying
3.7K
Gastric emptying occurs when the stomach gradually releases chyme into the duodenum. When the stomach is distended, it triggers the release of gastrin, a hormone that promotes gastric acid secretion to aid in digestion. Additionally, stomach distension contributes to peristaltic waves that propel gastric contents toward the pyloric region. The gastroenteric reflex, on the other hand, primarily stimulates peristalsis in the intestines, facilitating the movement of contents further along the...
3.7K
01:26Gastric Phase of Digestion
3.3K
The gastric phase of digestion begins as soon as food enters the stomach. The incoming food bolus triggers neural and hormonal mechanisms, which last approximately 3 to 4 hours. During this phase, the stomach undergoes significant changes to prepare the food for further digestion and absorption.
When food enters the stomach, it stretches the stomach walls and activates stretch receptors. This triggers local reflexes of the enteric nervous system, mediated through the myenteric plexus. These...
When food enters the stomach, it stretches the stomach walls and activates stretch receptors. This triggers local reflexes of the enteric nervous system, mediated through the myenteric plexus. These...
3.3K
01:16Focusing of Light in the Eye
5.8K
Light rays enter the eye through the cornea, a transparent dome-shaped tissue that is the eye's outermost layer. The cornea bends or refracts, light rays traveling to the pupil. The shape of the cornea determines how much of the light is bent and whether the image will be focused correctly on the retina at the back of the eye. Once the light has passed through both refraction layers, it converges into a single focal point onto a small area. This is where photoreceptors start transforming...
5.8K
01:27Coping Strategies: Problem Focused
503
Coping strategies are methods people use to manage, tolerate, or reduce the effects of stressors. These strategies involve both behavioral and psychological actions to handle stressful situations. One common approach is problem-focused coping, which aims to change or eliminate the source of stress rather than merely addressing its consequences. This method involves taking direct action to resolve the issue causing stress.
For example, consider a student who struggles to understand their...
For example, consider a student who struggles to understand their...
503
01:20Coping Strategies: Emotion Focused
518
Emotion-focused coping refers to a set of strategies aimed at managing the emotional impact of stressors, rather than directly addressing their causes. This approach involves altering one's emotional response to stressful situations to reduce their psychological effects. For example, individuals might talk with a friend or engage in activities like journaling to express their feelings. Such actions can help achieve emotional clarity or release, providing the psychological stability needed...
518