Related Experiment Video
Updated: Jan 30, 2026

Author Spotlight: Harnessing DNA Barcode Technology to Enhance the Efficiency of Medicinal Plant Identification
Published on: November 1, 2024
Taraxastane-type triterpenoids from the medicinal and edible plant Cirsium setosum
Peng-Cheng Lin1, Lin-Lin Ji2, Xiang-Jian Zhong2
1College of Pharmaceutical Sciences, Qinghai University for Nationalities, Xining 810000, China.
Abstract:
Guided by TNF-α secretion inhibitory activity assay, four taraxastane-type triterpenoids, including two new ones, 22-oxo-20-taraxasten-3β, 30-diol (1) and 22α-hydroxy-20-taraxasten-30β, 30-triol (2), have been obtained from an active fraction of the petroleum ether-soluble extract of the the medicinal and edible plant Cirsium setosum. Their structures were elucidated by spectroscopic data and CD data analysis. In the TNF-α secretion inhibitory activity assay, compounds 1 and 2 were active with the IC50 of 2.6 and 3.8 μmol·L-1, respectively. In addition, compounds 1 and 2 showed moderately selective cytotoxicity against the human ovarian cancer (A2780) and colon cancer (HCT-8) cell lines.
Related Concept Videos
Plant Cells and Tissues
Plant Cell Wall
Plant Tissue Culture
Plant Hormones
Tonicity in Plants
Plant Breeding and Biotechnology

