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[Eales' disease with neurologic disorders].

C Masson1, P Denis, S Prier

  • 1Hôpital Beaujon, Clichy.

Revue Neurologique
|January 1, 1988
PubMed
Summary
This summary is machine-generated.

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Two cases of Eale's disease with neurological symptoms were studied using magnetic resonance imaging (MRI). MRI revealed multifocal white matter abnormalities, raising questions about its association with multiple sclerosis or CNS vasculopathy.

Area of Science:

  • Neuro-ophthalmology
  • Neuroradiology
  • Neurology

Background:

  • Eale's disease is a rare retinal vasculitis.
  • Neurological involvement is uncommon but reported.
  • The nosological classification of Eale's disease with neurological complications is debated.

Observation:

  • Two patients with Eale's disease and neurological deficits were evaluated.
  • Case 1: Ocular diagnosis 10 years prior to cerebellar ataxia.
  • Case 2: Ocular findings followed 8 years later by myelopathy.

Findings:

  • Magnetic resonance imaging (MRI) was utilized for detailed neuroimaging.
  • Both patients exhibited multifocal white matter abnormalities on MRI.
  • The observed abnormalities suggest potential central nervous system (CNS) involvement.

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Implications:

  • The findings suggest a possible association between Eale's disease and multiple sclerosis.
  • Alternatively, the neurological manifestations could indicate a CNS vasculopathy affecting the retina.
  • Further research is needed to clarify the relationship between Eale's disease, CNS, and retinal vasculitis.