Related Experiment Video
Updated: Jan 30, 2026

Identification of Fatty Acids in Bacillus cereus
Published on: December 5, 2016
Commentary on the EMA Reflection Paper on the use of extrapolation in the development of medicines for paediatrics
Cécile Ollivier1, Andrew Thomson1, Efthymios Manolis1
1Human Medicines Research & Development Support Division, European Medicines Agency, London, UK.
Abstract:
Adopted guidelines reflect a harmonised European approach to a specific scientific issue and should reflect the most recent scientific knowledge. However, whilst EU regulations are mandatory for all member states and EU directives must be followed by national laws in line with the directive, EMA guidelines do not have legal force and alternative approaches may be taken, but these obviously require more justification. This new series of the BJCP, developed in collaboration with the EMA, aims to address this issue by providing an annotated version of some relevant EMA guidelines and regulatory documents by experts. Hopefully, this will help in promoting their diffusion and in opening a forum for discussion with our readers.
More Related Videos
Related Concept Videos
The Sense of Self: Reflected Self-Appraisal and Social Comparison
Reflection of Waves
Reflective Property of Parabolas
Microorganisms in Medicine and Therapeutics
Combination Therapies and Personalized Medicine
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
Total Internal Reflection Fluorescence Microscopy

