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Updated: Jan 30, 2026

Drug-Induced Sleep Endoscopy DISE with Target Controlled Infusion TCI and Bispectral Analysis in Obstructive Sleep Apnea
Published on: December 6, 2016
Establishing a Patent Nasal Passage in Obstructive Sleep Apnea
Chiba Shintaro1, Chan-Soon Park2
1Department of Otorhinolaryngology-Head and Neck Surgery, Jikei University School of Medicine, Tokyo, 105-8461 Japan.
Abstract:
The role of the nose in the pathophysiology and treatment of sleep-disordered breathing (SDB) has not been fully understood and might have been underestimated. In the Staring resistor model, the nose is regarded as a passive and noncollapsible tube, but recent studies have shown that the nose might participate more in the pathophysiology of SDB as anatomic, neuromuscular, and respiratory factors than previously reported, which might imply the nose is an active noncollapsible tube. The roles of nasal treatments for OSA are not only the reduction of AHI, but also the improvement of subjective symptoms, sleep quality, and CPAP adherence.
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