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Updated: Jan 29, 2026

Creating and Applying a Reference to Facilitate the Discussion and Classification of Proteins in a Diverse Group
Published on: August 16, 2017
[Comparison of UICC and AJCC 8th edition TNM classifications in uropathology]
Eva Compérat1, Justine Varinot1, Caroline Eymerit1
1Service d'anatomie et cytologie pathologiques, hôpital Tenon, HUEP, Sorbonne université, 4, rue de la Chine, 75020 Paris, France.
Abstract:
The pTNM stage is one of the most important parameters in the handling of tumor patients. The pathologist plays a major role in the determination of the stage. The classifications undergo an evolution according to the state of art. The TNM system is used worldwide and allows to precise the tumor (T) and lymph node stage and the presence of distant metastasis. This system helps to stratify patient groups and determine their prognosis. In 2017, the Union for International Cancer Control (UICC) and the American Joint Committee on Cancer (AJCC) published their 8th edition. Unluckily several differences exist between both classifications. The UICC neglected to make several recommendations according to the International Society of Urological Pathology (ISUP) decisions, which organises the consensus in uropathology.
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