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Yeast As a Chassis for Developing Functional Assays to Study Human P53
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Wild-Type p53 Promotes Cancer Metabolic Switch by Inducing PUMA-Dependent Suppression of Oxidative Phosphorylation

Jinchul Kim1, Lili Yu2, Wancheng Chen2

  • 1The Eighth Affiliated Hospital, Sun Yat-sen University, Shenzhen, Guangdong 518033, China; Cancer Research Institute, Guangdong Provincial Key Laboratory of Cancer Immunotherapy, School of Basic Medical Sciences, Southern Medical University, Guangzhou, Guangdong 510515, China; Division of Biological Sciences, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093-0322, USA.

Cancer Cell
|February 5, 2019
PubMed

Keywords:
PUMAglycolysismitochondriamitochondrial pyruvate carrieroxidative phosphorylationp53

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