Related Experiment Videos
Exploring the Interneuron Canopy Atop the 'Impenetrable Jungle'
Ramesh Chittajallu1, Carolina Bengtsson Gonzales1, Chris J McBain1
1Section on Cellular and Synaptic Physiology, Eunice Kennedy-Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, USA.
Trends in Neurosciences
|February 5, 2019
Abstract:
The multifaceted functions of the brain are borne through seemingly infinite spatiotemporal interactions between its resident neural elements. Using a combinatorial approach, Schuman and colleagues (J. Neurosci. 2018;39:125-139) recently identify four layer 1 cortical interneuron subtypes, including a hitherto uncharacterized neuron they term the 'canopy' cell. Properties unique to each of the subtypes likely endow them with distinct roles in top-down processing.