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Improving Polymethyl Methacrylate Resin Using a Novel Titanium Dioxide Coating.

Ghaith Darwish1, Su Huang2, Kent Knoernschild1

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Summary
This summary is machine-generated.

A novel atomic layer deposition (ALD) technique successfully coated poly (methyl methacrylate) (PMMA) with titanium dioxide (TiO2) nanoparticles. This TiO2 coating significantly reduced Candida albicans biofilm attachment, improving PMMA surface properties for better oral health.

Keywords:
C. albicans attachmentpoly methyl methacrylate resinsurface characterizationtitanium dioxide coating

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Area of Science:

  • Biomaterials Science
  • Surface Chemistry
  • Nanotechnology

Background:

  • Poly (methyl methacrylate) (PMMA) is widely used in dental prosthetics.
  • PMMA surfaces are susceptible to microbial adhesion and biofilm formation, impacting oral health.
  • Improving PMMA surface characteristics is crucial for enhancing denture hygiene and patient well-being.

Purpose of the Study:

  • To develop a novel thin film coating process for PMMA using atomic layer deposition (ALD).
  • To characterize the surface properties of ALD-coated PMMA, focusing on wettability, wear resistance, and antimicrobial activity.
  • To evaluate the stability and efficacy of the titanium dioxide (TiO2) coating on PMMA.

Main Methods:

  • ALD was employed to deposit a nano-thin TiO2 film on PMMA substrates.
  • Surface wettability was assessed via water contact angle measurements.
  • Wear resistance was evaluated using a mechanical toothbrushing device.
  • Chemical composition was analyzed using X-ray photoelectron spectroscopy (XPS).
  • Candida albicans biofilm attachment was quantified to assess antimicrobial efficacy.

Main Results:

  • A stable 30 nm TiO2 coating was successfully deposited on PMMA at 65°C.
  • The TiO2 coating significantly decreased surface wettability (water contact angle from 70° to <5°).
  • The coating remained intact after mechanical brushing and denture cleanser challenge.
  • Candida albicans attachment decreased by 63% to 77% on the TiO2-coated PMMA.
  • No significant difference in mechanical strength was observed between coated and uncoated PMMA.

Conclusions:

  • ALD is a viable technique for creating stable, adherent TiO2 thin films on PMMA.
  • The TiO2 coating enhances PMMA surface properties, reducing microorganism adhesion.
  • This surface modification holds potential for improving oral hygiene and health outcomes for denture wearers.