Related Experiment Video
Updated: Jan 29, 2026
06:25
Author Spotlight: Innovative Technique for Coronary Angiography in Marginal Donors
Published on: July 12, 2024
849
Hidden culprit lesion: beyond coronary angiography
Giovanni Lorenzoni1, Pierluigi Merella, Gavino Casu
1Unità Operativa Complessa di Cardiologia, Ospedale San Francesco, Nuoro, Italy.
Journal of Cardiovascular Medicine (Hagerstown, Md.)
|February 6, 2019
Insights
Coronary imaging helps detect coronary artery disease even without significant blockages. This technology aids in identifying vessel wall disease early for better patient outcomes.
Area of Science:
- Cardiovascular Imaging
- Interventional Cardiology
- Vascular Biology
Background:
- Obstructive coronary artery stenosis is traditionally identified using angiography.
- Non-obstructive coronary artery disease (CAD) poses diagnostic challenges.
- Advanced imaging modalities are crucial for comprehensive CAD assessment.
Observation:
- Coronary imaging techniques provide detailed visualization of the coronary vasculature.
- Vessel wall imaging can reveal atherosclerotic changes and inflammation.
- These findings are observable even when lumen narrowing is minimal.
Findings:
- Coronary imaging effectively identifies coronary wall disease.
- This is achievable even in cases lacking obstructive stenosis.
- Imaging highlights sub-clinical atherosclerosis and vessel remodeling.
Implications:
- Early detection of non-obstructive CAD can guide preventative strategies.
- Coronary imaging facilitates risk stratification in patients with suspected CAD.
- Understanding vessel wall disease improves therapeutic target identification.
Abstract:
: Coronary imaging is a useful tool to identify wall vessel disease also in the absence of obstructive stenosis.
Related Concept Videos
01:21Coronary Circulation
7.2K
The heart, an organ critical to survival, gets nourishment not from the blood it pumps but from a separate circulation system known as coronary circulation. This is the shortest circulation in the body and is responsible for supplying the heart with the nutrients it needs to function effectively.
Coronary circulation begins at the base of the aorta, where two main arteries arise—the left and right coronary arteries. These arteries encircle the heart in the coronary sulcus and supply the...
Coronary circulation begins at the base of the aorta, where two main arteries arise—the left and right coronary arteries. These arteries encircle the heart in the coronary sulcus and supply the...
7.2K
01:30Coronary Artery Disease I: Introduction
1.1K
Coronary Artery Disease (CAD): An Overview with Scientific InsightsCoronary Artery Disease (CAD), often referred to as C-A-D, is a prevalent blood vessel disorder classified under the broader category of atherosclerosis. Atherosclerosis is a pathological process characterized by the hardening and narrowing of arteries due to the accumulation of atherosclerotic plaques. These plaques are composed of cholesterol, fatty substances, inflammatory cells, calcium, and fibrin, reducing blood flow to...
1.1K
01:26Coronary Artery Disease II: Pathophysiology
426
Coronary Artery Disease (CAD) originates from a series of events that impair the function of coronary arteries, the blood vessels responsible for delivering oxygen-rich blood to the heart muscle. The pathophysiology of CAD is closely linked to atherosclerosis, a chronic inflammatory and lipid-driven condition affecting the vascular endothelium.1. Endothelial DamageThe process begins with damage to the vascular endothelium, which serves as a protective barrier between the blood and the vessel...
426
01:30Acute Coronary Syndrome I: Introduction
958
Acute Coronary Syndrome (ACS) encompasses a spectrum of heart conditions caused by sudden obstruction of coronary arteries, typically resulting from the rupture of an atherosclerotic plaque and subsequent thrombus (blood clot) formation. This obstruction can lead to partial or complete blockage of blood flow, causing varying degrees of myocardial ischemia or infarction.ACS includes the following clinical entities:Unstable Angina (UA)Non-ST-Elevation Myocardial Infarction (NSTEMI)ST-Elevation...
958
01:26Acute Coronary Syndrome V: Nursing Management
324
Nursing Assessment:Nursing management of acute coronary syndrome (ACS) involves taking the patient's history, focusing on primary complaints such as chest pain, dyspnea, and excessive sweating (diaphoresis), as well as other symptoms like back or jaw pain, nausea, vomiting, palpitations, dizziness, and fatigue. The nurse also reviews the patient's history of cardiac events, risk factors such as hypertension, diabetes, smoking, family history, and current medications.In the objective assessment,...
324
01:27Coronary Artery Disease V: Interprofessional Care
267
Interprofessional care for coronary artery disease includes pharmacological therapy and revascularization procedures.Pharmacological therapy for Coronary Artery Disease (CAD) aims to manage symptoms, prevent complications, and improve patient outcomes through various classes of medications:Antiplatelet Agents:Aspirin and Clopidogrel: These medications inhibit platelet aggregation, preventing blood clots, which is crucial for avoiding heart attacks and strokes. Doctors often prescribe these...
267