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Cognitive Functioning in Patients with Pediatric-Onset Multiple Sclerosis, an Updated Review and Future Focus
Joy B Parrish1, Emily Fields2,3
1Department of Neurology, Jacobs School of Medicine and Biomedical Sciences at the University at Buffalo, 1001 Main St., Buffalo, NY 14203, USA. jparrish@buffalo.edu.
Children (Basel, Switzerland)
|February 6, 2019
Summary
Pediatric-onset multiple sclerosis (POMS) impacts cognitive and psychosocial functioning in children. Advances in neuroimaging aid in identifying POMS and understanding its effects on the developing brain, necessitating further research.
Area of Science:
- Neurology
- Neuroimmunology
- Developmental Neuroscience
Background:
- Pediatric-onset multiple sclerosis (POMS) is a rare but increasingly identified condition.
- Advances in neuroimaging enhance the detection and understanding of multiple sclerosis (MS) in the developing brain.
- Existing literature consistently shows MS and demyelinating diseases affect cognitive and psychosocial development.
Purpose of the Study:
- To review cognitive and psychosocial functioning in pediatric-onset multiple sclerosis (POMS).
- To explore recent advancements in POMS research and their impact on outcomes.
- To highlight the need for future studies on deficits, disease correlates, prevention, and rehabilitation.
Main Methods:
- Literature review of studies on POMS.
- Analysis of findings related to cognitive and psychosocial functioning.
- Exploration of recent technological and neuroimaging advancements.
Main Results:
- Consistent evidence links MS and demyelinating diseases to impaired cognitive functioning and development.
- POMS significantly affects psychosocial functioning and daily living outcomes.
- Neuroimaging advances are improving POMS identification and understanding of brain impact.
Conclusions:
- Further research is crucial for understanding POMS-related deficits and disease correlates.
- Preventative strategies and rehabilitation approaches for POMS require focused investigation.
- A comprehensive understanding of POMS necessitates continued study of its multifaceted impacts.
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