Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Contact Angle

Contact Angle

When a solid is dipped inside a liquid, the liquid surface becomes curved near the contact. For some solid–liquid interfaces, the liquid is pulled up along the solid, while for others, the liquid surface is convex or depressed near the solid surface. This phenomenon can be explained using the concept of cohesive and adhesive forces.
The adhesive force is the molecular force between molecules of different materials, that is, between the molecules of the solid and the liquid. The cohesive...

Contact-dependent Signaling

Contact-dependent Signaling

Contact-dependent signaling, as the name suggests, requires that communicating cells be in direct contact with each other. This is achieved either through receptor-ligand interactions or by specialized cytoplasmic channels that allow the flow of small molecules between cells. In animal cells, channels called gap junctions facilitate contact-dependent signaling in certain tissues, whereas, plasmodesmata perform a similar function in plants.
Gap Junctions
In animal cells, gap junctions are formed...

Chronic Pharyngitis

Chronic Pharyngitis

Chronic pharyngitis refers to persistent inflammation of the pharyngial mucosa.
Etiology
It often arises from persistent viral or bacterial infections affecting sinuses and tonsils.
Additional contributing factors include inadequate dental hygiene, mouth breathing, recurring tonsillitis, allergic rhinitis, laryngopharyngeal reflux, and exposure to smoke, chemicals, and other environmental pollutants. Allergic reactions to pollen, mold, and pet dander, chronic cough, excessive voice usage,...

Transmission-based Precautions I: Contact, Enteric, and Droplets

Transmission-based Precautions I: Contact, Enteric, and Droplets

Transmission-based precautions are for patients known to be infected or suspected to be infected or colonized with organisms that pose a significant risk to others. Some transmission-based precautions include contact, enteric, and droplet.
Contact Precautions:
Contact precautions are the measures taken to prevent the transmission of infectious agents, especially epidemiologically important microorganisms such as MRSA or influenza, primarily transmitted through direct or indirect contact with an...

Chronic Pancreatitis I: Introduction

Chronic Pancreatitis I: Introduction

The pancreas, an elongated and flat gland situated behind the stomach, serves a vital function in digesting food and managing blood sugar levels.
Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...

Chronic Bowel Disorders: Introduction

Chronic Bowel Disorders: Introduction

Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Pharmacologic Alteration of Meibum Lipid Composition Alleviates Dry Eye Phenotype in Awat2-/- Mice.

Investigative ophthalmology & visual science·2026

Same author

Corneal Innervation Research at a Crossroads: A Tool-Driven Roadmap for the Future.

Investigative ophthalmology & visual science·2026

Same author

Cost-Effectiveness Analysis of Extended Depth of Focus Compared to Trifocal Intraocular Lens in Cataract Surgery.

American journal of ophthalmology·2026

Same author

A Cross-Species Hydroquinone Model Replicates Smoking-Related Corneal Endothelial Oxidative Injury and Enables Therapeutic Screening of FGF10.

Investigative ophthalmology & visual science·2026

Same author

Defining Discordance Between Signs and Symptoms in Dry Eye Disease: Insights From the DRy Eye Assessment and Management (DREAM) Study.

American journal of ophthalmology·2026

Same author

Hematopoietic Stem-Cell Gene Therapy for Cystinosis.

The New England journal of medicine·2026

Search research articles

Related Experiment Video

Updated: Jan 29, 2026

Simulating the Mechanics of Lens Accommodation via a Manual Lens Stretcher

Simulating the Mechanics of Lens Accommodation via a Manual Lens Stretcher

Published on: February 23, 2018

Chronic Conjunctivitis From a Retained Contact Lens.

Jawad I Arshad¹, Asma Saud, Darrell E White

¹Department of Ophthalmology and Visual Sciences (J.I.A., A.S., and R.R.S.), Case Western Reserve University and University Hospitals Eye Institute, Cleveland, OH; Skyvision Centers (D.E.W.), Westlake, OH; and Division of Cornea and Refractive Surgery (N.A.A.), Shiley Eye Institute, University of California San Diego, San Diego, CA.

Eye & Contact Lens

|February 7, 2019

Summary

This summary is machine-generated.

A retained soft contact lens can cause chronic bacterial conjunctivitis. Early diagnosis and removal of the lens, along with targeted antibiotics, are crucial for successful treatment, even with Gram-negative bacteria.

More Related Videos

Author Spotlight: Advancing Understanding of Age-Related Lens Stiffness Changes

Author Spotlight: Advancing Understanding of Age-Related Lens Stiffness Changes

Published on: April 5, 2024

Impression Cytology of the Lid Wiper Area

Impression Cytology of the Lid Wiper Area

Published on: August 9, 2016

Related Experiment Videos

Last Updated: Jan 29, 2026

Simulating the Mechanics of Lens Accommodation via a Manual Lens Stretcher

Simulating the Mechanics of Lens Accommodation via a Manual Lens Stretcher

Published on: February 23, 2018

Author Spotlight: Advancing Understanding of Age-Related Lens Stiffness Changes

Author Spotlight: Advancing Understanding of Age-Related Lens Stiffness Changes

Published on: April 5, 2024

Impression Cytology of the Lid Wiper Area

Impression Cytology of the Lid Wiper Area

Published on: August 9, 2016

Area of Science:

Ophthalmology
Microbiology

Background:

Unilateral chronic bacterial conjunctivitis can be recalcitrant to treatment.
Retained soft contact lenses are a rare but significant cause of persistent ocular infections.

Observation:

Three cases of unilateral recalcitrant chronic bacterial conjunctivitis associated with retained soft contact lenses were identified.
Gram-negative bacteria (Pseudomonas aeruginosa, Achromobacter xylosoxidans) and Gram-positive bacteria (Staphylococcus epidermidis) were isolated from the retained lenses.

Findings:

Successful treatment involved surgical removal of the retained contact lens and administration of targeted antibiotic eyedrop therapy.
Two of the three cases involved Gram-negative bacterial infections, a finding not previously emphasized in literature.

Implications:

Clinicians should suspect a retained contact lens in patients with chronic conjunctivitis, especially those with a history of contact lens wear.
Thorough ocular examination, including eyelid eversion, is essential for diagnosis.
Broad-spectrum antibiotic coverage is recommended due to the potential for Gram-negative pathogens.