Related Experiment Video
Updated: May 3, 2026
09:34
Microfluidic Pneumatic Cages: A Novel Approach for In-chip Crystal Trapping, Manipulation and Controlled Chemical Treatment
Published on: July 12, 2016
10.4K
Thinking Outside the "Blue Box": Induced Fit within a Unique Self-Assembled Polycationic Cyclophane
Arturo Blanco-Gómez1, Ángel Fernández-Blanco1, Víctor Blanco2
1Departamento de Química and Centro de Investigacións Científicas Avanzadas (CICA). Facultade de Ciencias , Universidade da Coruña , 15071 , A Coruña , Spain.
Journal of the American Chemical Society
|February 8, 2019
Summary
Researchers developed a novel "white box" molecular receptor that self-assembles in water. This pH-responsive host selectively binds aromatic substrates using multiple interaction types, offering versatile molecular recognition capabilities.
Area of Science:
- Supramolecular Chemistry
- Organic Chemistry
- Host-Guest Chemistry
Background:
- The
- blue box
Purpose of the Study:
- Develop a novel polycationic molecular receptor inspired by the cyclobis(paraquat-p-phenylene)cyclophane.
- Investigate the self-assembly, pH responsiveness, and substrate recognition capabilities of the new receptor.
Main Methods:
- Template-assisted self-assembly in water using acyl hydrazone bonding.
- Kinetic trapping to isolate the empty receptor.
- Characterization of macrocycle structure and properties.
- Evaluation of substrate binding using a combination of non-covalent interactions.
Main Results:
- The
- white box
Conclusions:
- The developed
- white box
Related Concept Videos
01:19Cyclic Processes And Isolated Systems
2.6K
A thermodynamic system with zero heat exchange and work is an isolated system. For these systems, the internal energy remains constant.
In the case of a non-isolated system, the change in the internal energy is zero only if the process is cyclic. A thermodynamic process is considered cyclic if the system undergoes a series of changes and returns to its initial state.
Consider a cyclic process that returns to its initial state, undergoing a four-step process. The heat transfer along each...
In the case of a non-isolated system, the change in the internal energy is zero only if the process is cyclic. A thermodynamic process is considered cyclic if the system undergoes a series of changes and returns to its initial state.
Consider a cyclic process that returns to its initial state, undergoing a four-step process. The heat transfer along each...
2.6K
01:28Induced Electric Dipoles
4.0K
A permanent electric dipole orients itself along an external electric field. This rotation can be quantified by defining the potential energy because the external torque does work in rotating it. Then, the potential energy is minimum at the parallel configuration and maximum at the antiparallel configuration. While the former is a stable equilibrium, the latter is an unstable equilibrium.
Since the absolute value of potential energy holds no physical meaning, its zero value can be chosen as per...
Since the absolute value of potential energy holds no physical meaning, its zero value can be chosen as per...
4.0K
01:26Spherical and Cylindrical Capacitor
5.4K
A spherical capacitor consists of two concentric conducting spherical shells of radii R1 (inner shell) and R2 (outer shell). The shells have equal and opposite charges of +Q and −Q, respectively. For an isolated conducting spherical capacitor, the radius of the outer shell can be considered to be infinite.
Conventionally, considering the symmetry, the electric field between the concentric shells of a spherical capacitor is directed radially outward. The magnitude of the field,...
Conventionally, considering the symmetry, the electric field between the concentric shells of a spherical capacitor is directed radially outward. The magnitude of the field,...
5.4K
01:31Dielectric Polarization in a Capacitor
5.5K
The presence of a dielectric medium in a capacitor not only changes the voltage and capacitance but also affects the electric field. In general, dielectrics can be of two types: polar and nonpolar. In a polar dielectric, the positive and negative charges in the molecules are separated by a distance and hence have a permanent dipole moment. In contrast, no such charge separation exists in a nonpolar dielectric, however the nonpolar molecules get polarized in the presence of an external electric...
5.5K
01:13Torque On A Current Loop In A Magnetic Field
5.6K
The most common application of magnetic force on current-carrying wires is in electric motors. These consist of loops of wire, which are placed between the magnets with a magnetic field. When current flows through the loops, the magnetic field applies torque, which causes the shaft to rotate, thus converting electrical energy to mechanical energy.
Consider a rectangular current-carrying loop containing N turns of wire, placed in a uniform magnetic field. The net force on a current-carrying loop...
Consider a rectangular current-carrying loop containing N turns of wire, placed in a uniform magnetic field. The net force on a current-carrying loop...
5.6K
01:27Induced Electric Fields: Applications
2.7K
An important distinction exists between the electric field induced by a changing magnetic field and the electrostatic field produced by a fixed charge distribution. Specifically, the induced electric field is nonconservative because it does not work in moving a charge over a closed path. In contrast, the electrostatic field is conservative and does no net work over a closed path. Hence, electric potential can be associated with the electrostatic field but not the induced field. The following...
2.7K