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Updated: Jan 29, 2026

Laser-assisted Microdissection LAM as a Tool for Transcriptional Profiling of Individual Cell Types
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An Improved Method for Cell Type-Selective Glycomic Analysis of Tissue Sections Assisted by Fluorescence Laser

Chiaki Nagai-Okatani1, Misugi Nagai2, Takashi Sato3

  • 1Glycoscience and Glycotechnology Research Group, Biotechnology Research Institute for Drug Discovery, National Institute of Advanced Industrial Science and Technology (AIST), Tsukuba, Ibaraki 305-8568, Japan. chiaki-okatani@aist.go.jp.

International Journal of Molecular Sciences
|February 10, 2019
PubMed
Summary

This study introduces a new method combining laser microdissection with lectin microarray analysis for cell-specific glycomic profiling in tissues. This technique enables precise analysis of glycan structures in specific cell populations for biomarker discovery.

Keywords:
glycomic profilingimmunohistochemistrylaser microdissectionlectin microarraytissue section

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