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Quantitative determination of eicosanoids in biological material
B A Peskar1, T Simmet, B M Peskar
1Dept. of Pharmacology and Toxicology, Ruhr-University, Bochum, FRG.
Abstract:
Radioimmunoassay is the most widely used method for determination of eicosanoids in biological material. Although this technique is, in principle, simple, radioimmunological data generally require extensive validation procedures. Here some examples for such methods are presented with special emphasis on the determination of cysteinyl-leukotrienes.