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Updated: Jan 29, 2026

Identifying Protein-protein Interaction Sites Using Peptide Arrays
Published on: November 18, 2014
Identifying Protein-DNA and Protein-Protein Interactions in Avian Embryos
Ana Paula Azambuja1, Marcos Simoes-Costa2
1Department of Molecular Biology and Genetics, Cornell University, Ithaca, NY, USA.
Abstract:
The chick embryo is a powerful model for experimental embryology due to its accessibility, sturdiness, and ease of manipulation. Here we describe protocols for analysis of protein-DNA and protein-protein interactions in tissues and cells isolated from the developing chick. These assays are aimed at the identification of interactions between transcription factors and regulatory elements in the genome, and, in combination with functional assays, can be used for the delineation of gene regulatory circuits.
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