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Updated: Jan 29, 2026

Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation
Published on: February 26, 2013
[Stroke as the first manifestation of atrial fibrillation]
Paweł Warmus1, Monika Adamczyk-Sowa1
1Katedra i Klinika Neurologii, Wydział Lekarski z Oddziałem Lekarsko- Dentystycznym w Zabrzu, Śląskiego Uniwersytetu, Medycznego w Katowicach, Zabrze, Polska.
Insights
Atrial fibrillation is a major cause of ischemic stroke, particularly in older adults. Early detection and long-term monitoring are crucial for timely anticoagulant therapy and improved patient outcomes.
Area of Science:
- Cardiology
- Neurology
- Geriatrics
Background:
- Atrial fibrillation is a leading cause of ischemic stroke, accounting for a significant portion of cardiogenic strokes.
- Undiagnosed atrial fibrillation, including paroxysmal and de novo forms, contributes to cryptogenic strokes.
- Population aging and improved diagnostics increase the prevalence and detection of atrial fibrillation.
Purpose of the Study:
- To emphasize the critical importance of diagnosing atrial fibrillation, especially de novo cases.
- To highlight the link between atrial fibrillation and increased stroke recurrence, mortality, and hospitalization.
- To advocate for enhanced diagnostic strategies for atrial fibrillation detection.
Main Methods:
- Review of existing literature on atrial fibrillation and ischemic stroke.
- Discussion of diagnostic tools, including Holter ECG monitoring.
- Emphasis on the value of long-term Holter ECG monitoring for detecting intermittent atrial fibrillation.
Main Results:
- Atrial fibrillation is a significant risk factor for ischemic stroke with poorer prognosis.
- A substantial percentage of atrial fibrillation cases remain undiagnosed.
- Long-term Holter monitoring is more effective than 24-h monitoring for detecting atrial fibrillation.
Conclusions:
- Timely diagnosis of atrial fibrillation is essential for initiating anticoagulant therapy (e.g., vitamin K antagonists, NOACs).
- Effective management of atrial fibrillation can mitigate stroke risk and improve patient outcomes.
- The study underscores the need for comprehensive diagnostic approaches to identify atrial fibrillation in stroke patients.
Abstract:
Atrial fibrillation is one of the most common causes of ischaemic stroke, especially among the elderly. Cardiogenic stroke accounts for approximately 15-25& of all ischaemic strokes, depending on different studies. About 1/3 of all ischaemic strokes have an unknown cause and it is estimated that paroxysmal atrial fibrillation contributes to cryptogenic ischaemic strokes. De novo atrial fibrillation accounts for even over 20& of ischaemic strokes. The number of patients with atrial fibrillation has probably increased due to the aging of the population and more precise diagnostic procedures. Detection of atrial fibrillation is of great importance because ischaemic stroke due to atrial fibrillation is characterized by a tendency to recurrence, worse prognosis, longer hospitalization and higher mortality. Atrial fibrillation remains undiagnosed in a large percentage of cases. Holter ECG monitoring is most often used for diagnostic purposes. However, the diagnostic process should also include long-term Holter ECG monitoring because atrial fibrillation is detected only in a small percentage of cases when 24-h ECG monitoring is used. Our paper stresses the fact that the diagnosis of atrial fibrillation, particularly de novo, is very important for further therapeutic treatment i.e. the use of anticoagulants i.e. both the antagonists of vitamin K and NOACs.
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