Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Ethical Issues01:27

Ethical Issues

2.2K
Nurses are essential in patient care, upholding the ethical principles of their profession and effectively navigating ethical dilemmas. Neglecting ethical issues can lead to inadequate patient care, compromised therapeutic relationships, and moral distress among healthcare workers.
Ethical Concerns in Healthcare:
2.2K
Lethal Alleles02:41

Lethal Alleles

18.0K
Agouti: A Lethal Allele
Lucien Cuénot discovered lethal alleles in 1905 while studying the inheritance of coat color in mice. The agouti gene is responsible for the color of the coat in mice. This gene codes for an agouti-signaling protein, which is responsible for melanin distribution in mammals. The wild-type allele gives rise to gray-brown coat color in mice, while the mutant allele gives rise to yellow coat color. In addition to coat color, the agouti gene is associated with the yellow...
18.0K
Issues And Trends In Healthcare Delivery System01:29

Issues And Trends In Healthcare Delivery System

6.3K
The issues and trends in healthcare delivery are constantly changing. The COVID-19 pandemic is one recent issue that wreaked havoc on healthcare systems, causing a shortage of healthcare workers, high demand for medicines and supplies, and increased medical expenditure due to a lack of insurance. Other issues include rising healthcare costs and care fragmentation.
Cost Containment
Payment for healthcare services has historically promoted adoption of costly and often unnecessary or inefficient...
6.3K
Appendicitis-II: Diagnostic Studies and Management01:29

Appendicitis-II: Diagnostic Studies and Management

562
Diagnosing and managing appendicitis requires a structured and comprehensive approach that spans from initial assessment to postoperative care. Here is an overview of the process:
Diagnosing Appendicitis
It requires a multifaceted approach, starting with a detailed physical examination to pinpoint the location and nature of the pain and identify any associated symptoms. Laboratory tests play a crucial role. A complete Blood Count (CBC) typically reveals leukocytosis (an increased number of...
562
Myasthenia Gravis: Diagnostic Tests01:15

Myasthenia Gravis: Diagnostic Tests

2.4K
Myasthenia gravis is an autoimmune condition affecting neuromuscular transmission, causing generalized weakness in skeletal muscles. Initial diagnoses rely on patients' signs, symptoms, and medical history. The challenge lies in distinguishing myasthenia from other muscular dystrophies. An important diagnostic feature is the significant improvement of symptoms after administering anticholinesterase inhibitors.
The edrophonium test is a diagnostic tool for myasthenia gravis. It involves...
2.4K
Asthma-IV: Diagnostic and Management01:30

Asthma-IV: Diagnostic and Management

3.1K
The diagnosis and management of asthma are comprehensive, encompassing clinical assessments, lung function tests, and pharmacological interventions. Here's an overview:
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
3.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Genetic testing in sudden infant death - a wolf in sheep's clothing?

Forensic science, medicine, and pathology·2018
Same author

Unusual osteological findings in sacred relics from the LESJE monastery in central Serbia.

Forensic science, medicine, and pathology·2018
Same author

Infants who die in shared sleeping situations differ from those who die while sleeping alone.

Acta paediatrica (Oslo, Norway : 1992)·2018
Same author

Characteristic "neck collar" injuries in Australian sea lions (Neophoca cinerea) caused by marine debris.

Forensic science, medicine, and pathology·2018
Same author

Systemic Dissemination of Injected Foreign Material.

Journal of forensic sciences·2018
Same author

Scurvy-Characteristic Features and Forensic Issues.

The American journal of forensic medicine and pathology·2018

Related Experiment Video

Updated: Jan 29, 2026

Enhanced Genetic Analysis of Single Human Bioparticles Recovered by Simplified Micromanipulation from Forensic ‘Touch DNA’ Evidence
11:49

Enhanced Genetic Analysis of Single Human Bioparticles Recovered by Simplified Micromanipulation from Forensic ‘Touch DNA’ Evidence

Published on: March 9, 2015

16.7K

Lethal strongyloidiasis - Diagnostic and forensic issues.

Roger W Byard1

  • 1School of Medicine, Level 2 Medical School North Building, The University of Adelaide, Frome Road, Forensic Science South Australia (FSSA), Adelaide, 5005, SA, Australia.

Journal of Forensic and Legal Medicine
|February 10, 2019
PubMed
Summary
This summary is machine-generated.

Strongyloidiasis, caused by Strongyloides stercoralis, affects millions globally. This parasitic infection can remain asymptomatic for decades before potentially causing lethal hyperinfection syndrome under immunosuppression.

Keywords:
DeathDisseminationForensicHyperinfectionSteroid therapyStrongyloides stercoralisStrongyloidiasis

More Related Videos

Scanning Skeletal Remains for Bone Mineral Density in Forensic Contexts
07:56

Scanning Skeletal Remains for Bone Mineral Density in Forensic Contexts

Published on: January 29, 2018

18.3K
A Data Integration Workflow to Identify Drug Combinations Targeting Synthetic Lethal Interactions
07:40

A Data Integration Workflow to Identify Drug Combinations Targeting Synthetic Lethal Interactions

Published on: May 27, 2021

4.6K

Related Experiment Videos

Last Updated: Jan 29, 2026

Enhanced Genetic Analysis of Single Human Bioparticles Recovered by Simplified Micromanipulation from Forensic ‘Touch DNA’ Evidence
11:49

Enhanced Genetic Analysis of Single Human Bioparticles Recovered by Simplified Micromanipulation from Forensic ‘Touch DNA’ Evidence

Published on: March 9, 2015

16.7K
Scanning Skeletal Remains for Bone Mineral Density in Forensic Contexts
07:56

Scanning Skeletal Remains for Bone Mineral Density in Forensic Contexts

Published on: January 29, 2018

18.3K
A Data Integration Workflow to Identify Drug Combinations Targeting Synthetic Lethal Interactions
07:40

A Data Integration Workflow to Identify Drug Combinations Targeting Synthetic Lethal Interactions

Published on: May 27, 2021

4.6K

Area of Science:

  • Infectious Diseases
  • Parasitology
  • Global Health

Background:

  • Strongyloidiasis affects 30-100 million people worldwide, primarily caused by the nematode Strongyloides stercoralis.
  • The infection is characterized by a chronic asymptomatic carrier state due to autoinfection, which can persist for decades.
  • Immunosuppression can trigger dissemination and the lethal hyperinfection syndrome.

Purpose of the Study:

  • To highlight the diagnostic challenges and increasing incidence of Strongyloidiasis.
  • To underscore the potential for severe outcomes, particularly hyperinfection syndrome.
  • To raise awareness in non-endemic areas and among populations with increased mobility.

Main Methods:

  • This abstract is based on a review of existing literature and clinical observations.
  • Diagnostic criteria and autopsy findings are discussed.
  • The role of host factors and environmental influences on disease progression are examined.

Main Results:

  • Strongyloides stercoralis exhibits unique autoinfection capabilities, leading to prolonged asymptomatic carriage.
  • Hyperinfection syndrome, often fatal, is precipitated by immunosuppression (e.g., steroid therapy, HTLV-1).
  • Autopsy findings include gastrointestinal ulceration, hemorrhage, and pulmonary damage.

Conclusions:

  • Strongyloidiasis poses a significant global health burden with diagnostic difficulties, especially in non-endemic regions.
  • The increasing incidence necessitates heightened clinical suspicion and improved diagnostic strategies.
  • Understanding the pathogenesis is crucial for managing this potentially lethal parasitic infection.