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Updated: Jan 29, 2026

Personalized Peptide Arrays for Detection of HLA Alloantibodies in Organ Transplantation
Published on: September 6, 2017
[Size Estimation of HLA -Ⅰ class Typed Platelet Apheresis Donor Bank]
Min Xue1, Qin-Qin Pan2, Su Fan2
1Jiangsu Province Blood Center,Nanjing 210042,Jiangsu Province, China.E-mail:13905185030@163.com.
Objective:
To estimate the size of HLA -Ⅰ class typed platelet apheresis donor bank.
Methods:
A total of 16062 blood samples from Chinese Han voluntary unrelated marrow donors in Jiangsu were included in this study. Luminex-SSO was used to detect the HLA -Ⅰ class(A,B locus) antigens. The probability of finding at least one HLA matched unrelated donor was calculated based on the HLA -I class phenotype frequency.
Results:
The population genetic data of HLA -Ⅰ class in Jiangsu were obtained, the optinal bans size in HLA typed apheresis plateler donor registry databane hrad been estimated by evaluating the population genetic data of HLA-1 class same donor.
Conclusion:
The establishment of HLA-1 class typed apheresis platelet donor bank with a total size of 1500 persons is acceptable, which can satisty the patients with phenotype freguency>0.002 to find at least 1 phenotype same donor in 95% probavility.
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